Healing protein injection could ease back pain without surgery
NCT ID NCT07668466
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a new medicine called CBT005, a healing protein injected directly into damaged spinal discs. The goal is to see if it is safe and can reduce long-term back pain in 60 adults with disc degeneration. Participants get one injection and are followed for up to 3 years.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Growth differentiation factor 6 (CBT005)
What this could lead to
If it works, this could offer a new injection-based treatment for chronic back pain caused by damaged discs, potentially reducing the need for surgery.
What could go wrong
This is an early phase 1/2 trial with only 60 people, so it is too soon to know if it is truly effective or safe. The injection itself carries risks like infection or nerve damage.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Spine & Scoliosis Service
Kogarah, New South Wales, 2217, Australia
Contact Phone: •••-•••-•••• Email: •••••@•••••