Can talk therapy for sleep beat cancer fatigue?

NCT ID NCT05226078

Ongoing Symptom relief Sponsor: Abramson Cancer Center at Penn Medicine Source: ClinicalTrials.gov ↗

First seen Aug 21, 2026 · Last updated Aug 21, 2026

Summary

This trial tests whether cognitive behavioral therapy for insomnia (CBT-I) can reduce cancer-related fatigue in breast cancer patients who also have chronic insomnia. Participants receive different doses of CBT-I, which focuses on changing sleep habits and thoughts. The study aims to see if the therapy is acceptable, feasible, and effective in improving sleep and fatigue.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Cognitive Behavioral Therapy for Insomnia (CBT-I)
What this could lead to: If effective, this could point toward a tailored, non-drug approach to reduce fatigue and improve sleep in breast cancer patients.
What could go wrong: This is an early-stage trial with a small number of participants, so results may not apply broadly. The therapy requires commitment, and benefits may vary.

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Conditions

The condition(s) this trial relates to.

breast cancer cancer-related condition Fatigue insomnia neoplasm neoplastic syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

University of Pennsylvania

Philadelphia, Pennsylvania, 19104, United States

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Other studies related to the condition(s) this trial covers.