Can online therapy stop insulin resistance in HIV patients? new trial aims to find out
NCT ID NCT07226128
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether an internet-based depression treatment called cognitive behavioral therapy (iCBT-D) can prevent insulin resistance from getting worse in adults with HIV who are on antiretroviral therapy and have depression. Researchers will compare the online therapy program to standard depression education in 150 participants over 12 months. The goal is to see if treating depression improves how the body uses insulin and reduces inflammation.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- internet-based cognitive behavioral therapy (iCBT-D)
- What this could lead to
- If successful, this could show that treating depression with online therapy helps prevent insulin resistance and related health problems in people with HIV.
- What could go wrong
- This is a small, early-stage trial with only 150 participants, so results may not apply widely. The therapy may not improve insulin resistance as hoped.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for COGNITIVE BEHAVIOR THERAPY are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Indiana University Health
RECRUITINGIndianapolis, Indiana, 46202, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- A fiber supplement may help perimenopausal women — a trial puts it to the test
- Small cash rewards may keep HIV-positive mothers in treatment — a trial puts the idea to the test
- Choice may boost HIV prevention: a trial tests offering multiple PrEP options to young women in kenya
- Home care plus nutrition may cut post-hospital deaths in HIV — a trial puts it to the test
- Heavy drinking and risky sex: a text-based intervention aims to cut HIV risk
- Pharmacists on the front line: a new strategy to fight heart disease in people with HIV