Can CBD replace antipsychotics for cannabis users with psychosis?

NCT ID NCT04105231

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study compares cannabidiol (CBD) to the standard antipsychotic risperidone in 64 adults with schizophrenia or related psychotic disorders who have used cannabis. The goal is to see if CBD can reduce psychotic symptoms and help people stop or cut down cannabis use. Participants receive either CBD or risperidone for several weeks, and their symptoms and cannabis use are tracked.

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Conditions

The condition(s) this trial relates to.

cannabis dependence drug psychosis paranoid schizophrenia Psychotic Disorders schizoaffective disorder schizophrenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Center for Neuropsychiatric Schizophrenia Research

    Glostrup Municipality, 2600, Denmark