CBD shows promise in curbing opioid cravings
NCT ID NCT03787628
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether cannabidiol (CBD) can reduce cravings and prevent relapse in people with opioid use disorder who are already taking standard medications like buprenorphine or methadone. Thirty-five participants received either CBD or a placebo for 28 days while in residential treatment. Researchers tracked side effects, cravings, and drug use through questionnaires and urine tests over a 10-week period.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Cannabidiol (CBD)
What this could lead to
If it works, CBD could become an add-on treatment to help people with opioid use disorder stay in recovery and avoid relapse.
What could go wrong
This was a small, early-phase study with only 35 participants, so results may not apply broadly. CBD may not reduce craving or prevent relapse better than placebo.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Tarzana Treatment Centers
Tarzana, California, 91356, United States