Could CBD and CBN ease your jaw pain and headaches?

NCT ID NCT05961501

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether a drink containing CBD and CBN can reduce facial pain and headaches caused by muscle tension. 42 adults with pain lasting over 3 months will be randomly assigned to receive either the CBD/CBN drink or a placebo. Researchers will measure pain and muscle activity over 60 days to see if the treatment helps.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

cannabidiol (CBD) and cannabinol (CBN) oral solution

What this could lead to

If it works, this could point toward a new, natural option for managing chronic facial pain and tension headaches.

What could go wrong

This is a small, early-phase trial with only 42 people, so results may not apply to everyone. The study is also placebo-controlled, so any benefit might be due to the placebo effect.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Facial Pain Headache headache disorder Myalgia myofascial pain syndrome Tension-Type Headache

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Wroclaw Medical University

    Wroclaw, 50-425, Poland