Could CBD and CBN ease your jaw pain and headaches?

NCT ID NCT05961501

ENROLLING_BY_INVITATION Symptom relief Sponsor: Wroclaw Medical University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether a drink containing CBD and CBN can reduce facial pain and headaches caused by muscle tension. 42 adults with pain lasting over 3 months will be randomly assigned to receive either the CBD/CBN drink or a placebo. Researchers will measure pain and muscle activity over 60 days to see if the treatment helps.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: cannabidiol (CBD) and cannabinol (CBN) oral solution
What this could lead to: If it works, this could point toward a new, natural option for managing chronic facial pain and tension headaches.
What could go wrong: This is a small, early-phase trial with only 42 people, so results may not apply to everyone. The study is also placebo-controlled, so any benefit might be due to the placebo effect.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Facial Pain Headache headache disorder Myalgia myofascial pain syndrome Tension-Type Headache

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEADACHE HEADACHE, TENSION HEADACHES MUSCULAR MUSCLE PAIN MYALGIA OROFACIAL PAIN

Could CBD and CBN ease your jaw pain and headaches?

Summary

What this could mean

Get notified about this study

Conditions

As listed by the trial registrant

Contacts and locations

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