Engineered immune cells take on recurrent brain tumors in early trial

NCT ID NCT07209241

First seen Nov 01, 2025 · Last updated Jun 11, 2026 · Updated 32 times

Summary

This early-phase study tests a new treatment for a type of brain cancer (glioblastoma) that has come back after standard therapy. The treatment uses the patient's own immune cells, which are modified in a lab to recognize and attack the cancer. The main goal is to check the safety of this approach in 12 adults whose tumors have a specific genetic change (EGFR amplification).

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • University of Pennsylvania

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.