New hope for kids with tough cancers: drug combo tested in small study
NCT ID NCT02512926
First seen Nov 01, 2025 · Last updated May 19, 2026 · Updated 28 times
Summary
This early-phase study tested a new drug, carfilzomib, combined with two standard chemotherapy drugs (cyclophosphamide and etoposide) in 4 children whose solid tumors or leukemia had returned or not responded to prior treatments. The main goal was to find the safest dose and understand side effects. The study was completed but did not aim to cure the disease; it focused on controlling the cancer and gathering safety information.
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This is a summary of
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Alberta Children's Hospital
Calgary, Alberta, T3B 6A8, Canada
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Arkansas Children's Hospital
Little Rock, Arkansas, 72202, United States
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Dana Farber Cancer Institute
Boston, Massachusetts, 02215, United States
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Memorial Sloan-Kettering Cancer Center
New York, New York, 10065, United States
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Penn State Hershey Children's Hospital
Hershey, Pennsylvania, 17033-0850, United States
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Phoenix Children's Hospital
Phoenix, Arizona, 85016, United States
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Stanford University School of Medicine and Stanford Cancer Institute
Palo Alto, California, 94304, United States
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University of Texas Health Science Center at San Antonio
San Antonio, Texas, 78229, United States
Conditions
Explore the condition pages connected to this study.