New procedure aims to zap nerves to fix slow heartbeat

NCT ID NCT07468383

Recruiting now Disease control Sponsor: Beijing Anzhen Hospital Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a procedure called cardioneuroablation for people with a slow heart rate (bradycardia) caused by overactive vagal nerves. Doctors use a catheter to ablate (destroy) specific nerve clusters in the heart. The trial will enroll 188 participants aged 18-65 and measure changes in average heart rate and quality of life. The goal is to see if this can reduce symptoms like dizziness and fatigue without needing a pacemaker.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: cardioneuroablation (catheter procedure to ablate cardiac nerve clusters)
What this could lead to: If successful, this procedure could offer a non-drug, non-pacemaker option to control symptoms of slow heart rate caused by overactive vagal nerve activity.
What could go wrong: This is an early-stage study with no phase designation, so results are uncertain. The procedure is invasive and carries risks like bleeding, infection, or heart rhythm issues.

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Conditions

The condition(s) this trial relates to.

autonomic nervous system disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AUTONOMIC NERVOUS SYSTEM DISEASES SYMPTOMATIC BRADYCARDIA

Contacts and locations

Locations

Beijing Anzhen Hospital, Capital Medical University
RECRUITING

Beijing, China, 100029, China

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