New procedure aims to zap nerves to fix slow heartbeat

NCT ID NCT07468383

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a procedure called cardioneuroablation for people with a slow heart rate (bradycardia) caused by overactive vagal nerves. Doctors use a catheter to ablate (destroy) specific nerve clusters in the heart. The trial will enroll 188 participants aged 18-65 and measure changes in average heart rate and quality of life. The goal is to see if this can reduce symptoms like dizziness and fatigue without needing a pacemaker.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

cardioneuroablation (catheter procedure to ablate cardiac nerve clusters)

What this could lead to

If successful, this procedure could offer a non-drug, non-pacemaker option to control symptoms of slow heart rate caused by overactive vagal nerve activity.

What could go wrong

This is an early-stage study with no phase designation, so results are uncertain. The procedure is invasive and carries risks like bleeding, infection, or heart rhythm issues.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

autonomic nervous system disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beijing Anzhen Hospital, Capital Medical University

    RECRUITING

    Beijing, China, 100029, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact