Hidden heart condition may be common in seniors with heart failure

NCT ID NCT06427304

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how often cardiac amyloidosis—a condition where abnormal proteins build up in the heart—occurs in people aged 80 and older who have been hospitalized for heart failure. Researchers will use bone scans to detect the condition in 637 participants. The goal is to find out how many of these older patients have undiagnosed cardiac amyloidosis, which could help improve future screening and care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could show that cardiac amyloidosis is a common, hidden cause of heart failure in older adults, leading to better screening and earlier diagnosis.
What could go wrong
This is an observational study, not a treatment trial. It will not test any therapy, and the results may not apply to all older adults with heart failure.

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Conditions

The condition(s) this trial relates to.

Amyloid Neuropathies, Familial amyloidosis heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Ambroise Paré Hospital

    RECRUITING

    Boulogne-Billancourt, Île-de-France Region, 92100, France

  • Bretonneau Hospital

    RECRUITING

    Paris, Île-de-France Region, 75018, France

  • CHRU Nancy

    RECRUITING

    Nancy, 54000, France

  • CHRU Tours-Bretonneau Hospital

    RECRUITING

    Tours, 37000, France

  • CHU Amiens Picardie

    RECRUITING

    Amiens, 80000, France

  • CHU Angers

    RECRUITING

    Angers, 49100, France

  • CHU Bordeaux

    RECRUITING

    Bordeaux, 33000, France

  • CHU Dijon

    RECRUITING

    Dijon, 21000, France

  • CHU Grenoble Alpes

    RECRUITING

    Grenoble, 38700, France

  • CHU Lille

    RECRUITING

    Lille, 59000, France

  • CHU Limoges

    RECRUITING

    Limoges, 87000, France

  • CHU Lyon

    RECRUITING

    Lyon, 69002, France

  • CHU Marseille

    RECRUITING

    Marseille, 13005, France

  • CHU Montpellier

    RECRUITING

    Montpellier, Occitanie, 34090, France

  • CHU Nantes

    RECRUITING

    Nantes, Loire-Atlantique, 44000, France

  • CHU Nice

    RECRUITING

    Nice, 06000, France

  • CHU Orléans

    RECRUITING

    Orléans, 45100, France

  • CHU Poitiers

    RECRUITING

    Poitiers, New Aquitaine, 86000, France

  • CHU Rennes

    RECRUITING

    Rennes, 35000, France

  • CHU Rouen, Charles Nicole hospital

    RECRUITING

    Rouen, Normandy, 76000, France

  • CHU Toulouse

    RECRUITING

    Toulouse, Occitanie, 31300, France

  • CHU Trousseau-Tours

    RECRUITING

    Chambray-lès-Tours, 37170, France

  • Centre Hospitalier Intercommunal de Castres-Mazamet

    RECRUITING

    Castres, 81100, France

  • Centre Hospitalier de Carcassonne

    RECRUITING

    Carcassonne, 11100, France

  • Charles Foix Hospital

    RECRUITING

    Ivry-sur-Seine, Île-de-France Region, 94200, France

  • Clinique Saint Joseph Trelaze

    RECRUITING

    Trélazé, 49800, France

  • Clinique du Millénaire-Montpellier

    RECRUITING

    Montpellier, 34000, France

  • Corentin Celton Hospital

    NOT_YET_RECRUITING

    Issy-les-Moulineaux, Île-de-France Region, 92130, France

  • Emile Roux Hospital

    RECRUITING

    Limeil-Brévannes, Île-de-France Region, 94450, France

  • Europeen Georges Pompidou Hospital

    RECRUITING

    Paris, Île-de-France Region, 75015, France

  • GH Sud Ile-de-France

    RECRUITING

    Melun, Île-de-France Region, 77000, France

  • Geriatric Department, Broca Hospital

    RECRUITING

    Paris, IIe-de-France, 75013, France

  • Hôpital Privé Gériatrique LES SOURCES-Nice

    RECRUITING

    Nice, 06100, France

  • Lariboisière Hospital

    RECRUITING

    Paris, Île-de-France Region, 75010, France

  • Médipôle Hôpital Mutualiste Villeurbanne

    RECRUITING

    Villeurbanne, 69100, France

  • Saint Joseph Hospital

    RECRUITING

    Paris, Île-de-France Region, 75014, France

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