New hope for kids with aggressive brain tumors: pioneering therapy delivered directly to the brain

NCT ID NCT05835687

Summary

This early-stage study is testing a new type of personalized immune therapy called B7-H3-CAR T cells for children and young adults (up to age 21) with brain tumors that have come back or haven't responded to standard treatments. The therapy involves collecting a patient's own immune cells, modifying them in a lab to target a protein on the tumor, and then infusing them directly into the fluid around the brain and spinal cord. The main goal is to find the safest dose of this new treatment.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • St. Jude Children's Research Hospital

    RECRUITING

    Memphis, Tennessee, 38105, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.