Marijuana and HIV drugs: a risky mix or safe combo?
NCT ID NCT04800159
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at how cannabis (marijuana) affects the levels of HIV medications in the blood and brain, as well as mood and thinking. Researchers will give cannabis or a placebo to 40 people with HIV to see if it changes how their drugs work. The goal is to understand if cannabis use is safe for people on HIV treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Cannabis (THC and CBD)
What this could lead to
If successful, this study could help doctors understand whether cannabis is safe to use with HIV medications and how it might affect treatment.
What could go wrong
This is a small, early-stage study (Phase 2) with only 40 people receiving cannabis. Results may not apply to everyone, and the study looks at drug levels, not long-term health outcomes.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Ucsd Hnrp-Cmcr
San Diego, California, 92103, United States