Can cannabis calm restless legs? new study aims to find out

NCT ID NCT06863740

First seen Apr 29, 2026 · Last updated Jun 19, 2026 · Updated 9 times

Summary

This pilot study will test whether cannabis oil can safely help people with restless legs syndrome (RLS). Thirty adults with moderate-to-severe RLS will receive either cannabis oil or a placebo for 8 weeks. Researchers will track side effects, how many people finish the study, and changes in sleep and quality of life.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Sunnybrook Health Sciences Centre

    RECRUITING

    Toronto, Ontario, M4N3M5, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Health Network

    RECRUITING

    Toronto, Ontario, M5G 2C4, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

cannabis oil (5:1 CBD:THC)

What this could lead to

If it works, this could point toward a new treatment option for restless legs syndrome that improves sleep and quality of life.

What could go wrong

This is a very small, early pilot study focused on safety and feasibility, not effectiveness. It may not show clear benefits, and cannabis can cause side effects like drowsiness or dizziness.

Conditions

The condition(s) this trial relates to.

restless legs syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.