RESTLESS LEG SYNDROME (RLS)
Clinical trials for RESTLESS LEG SYNDROME (RLS) explained in plain language.
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Cannabis oil put to the test for restless legs in First-Ever controlled trial
Symptom relief Recruiting nowThis pilot study will test whether cannabis oil is safe and feasible for treating restless legs syndrome (RLS). Thirty adults with moderate-to-severe RLS will receive either cannabis oil (with a 5:1 ratio of CBD to THC) or a placebo for 8 weeks. Researchers will track side effect…
Matched conditions: RESTLESS LEG SYNDROME (RLS)
Phase: NA • Sponsor: Sunnybrook Health Sciences Centre • Aim: Symptom relief
Last updated Jun 27, 2026 12:24 UTC
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New pill could quiet restless legs – early trial underway
Symptom relief Recruiting nowThis early-stage study is testing a new calcium channel modulator to see if it can ease symptoms of Restless Legs Syndrome (RLS). About 20 adults with moderate-to-severe RLS will take the drug twice a day for 12 weeks. Researchers will measure changes in symptom severity and watc…
Matched conditions: RESTLESS LEG SYNDROME (RLS)
Phase: PHASE1 • Sponsor: Beijing Friendship Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 09:11 UTC
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Could a simple nerve zap soothe restless legs in pregnancy?
Symptom relief Recruiting nowThis study tests a small, non-invasive device that stimulates a nerve in the leg to see if it can safely ease Restless Legs Syndrome (RLS) during pregnancy. Fifteen pregnant women between 21 and 26 weeks will use the device for 30-minute sessions over 8 weeks. Researchers will ch…
Matched conditions: RESTLESS LEG SYNDROME (RLS)
Phase: NA • Sponsor: Rhode Island Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 07:57 UTC
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Could spinal cord stimulators calm restless legs? new study investigates
Knowledge-focused Recruiting nowThis study looks at how spinal cord stimulators affect nerve signals and symptoms in people with Restless Leg Syndrome (RLS). Researchers will measure brain and nerve activity using EEG, EMG, and other tests while the stimulator is on or off. The study includes 50 participants, s…
Matched conditions: RESTLESS LEG SYNDROME (RLS)
Phase: NA • Sponsor: University of Alabama at Birmingham • Aim: Knowledge-focused
Last updated Jun 28, 2026 00:00 UTC
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Scientists probe gene changes behind RLS drug side effects
Knowledge-focused Recruiting nowThis study tracks gene changes in people with Restless Legs Syndrome who take dopamine agonists for different lengths of time. Researchers will collect nasal swabs from 50 participants—some new to the drugs, others on them for 6+ months—to see how key genes change. The goal is to…
Matched conditions: RESTLESS LEG SYNDROME (RLS)
Sponsor: HBC Immunology Inc • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:38 UTC