Scientists test Triple-Threat drug combo against Tough-to-Treat cancers
NCT ID NCT02496208
Summary
This early-stage study is testing the safety and best doses of a combination of cancer drugs for people with advanced cancers of the urinary system (like bladder and kidney cancer) that have spread. The trial combines a pill (cabozantinib) that aims to block tumor growth with one or two immunotherapy drugs (nivolumab and ipilimumab) that aim to help the body's immune system fight the cancer. The main goal is to find out how much of each drug can be given safely together.
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Contacts and locations
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Locations
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City of Hope Comprehensive Cancer Center
Duarte, California, 91010, United States
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Los Angeles General Medical Center
Los Angeles, California, 90033, United States
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NCI - Center for Cancer Research
Bethesda, Maryland, 20892, United States
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National Institutes of Health Clinical Center
Bethesda, Maryland, 20892, United States
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Ohio State University Comprehensive Cancer Center
Columbus, Ohio, 43210, United States
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Rutgers Cancer Institute of New Jersey
New Brunswick, New Jersey, 08903, United States
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USC / Norris Comprehensive Cancer Center
Los Angeles, California, 90033, United States
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University of California Davis Comprehensive Cancer Center
Sacramento, California, 95817, United States
Conditions
Explore the condition pages connected to this study.