Can a common cholesterol drug shield the heart after lung surgery?

NCT ID NCT07727681

First seen Jul 27, 2026 · Last updated Jul 29, 2026 · Updated 2 times

Summary

This trial investigates whether a short course of atorvastatin, a widely used statin, can prevent atrial fibrillation—a rapid, irregular heartbeat—in adults aged 60 and older undergoing lung surgery. Participants are randomly assigned to receive either atorvastatin or a placebo for a few days before and after their operation. The study uses continuous heart monitoring for 72 hours after surgery to detect any abnormal rhythms, aiming to see if this simple intervention can reduce a common postoperative complication.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
atorvastatin (a statin drug) given as 40 mg daily before and after lung surgery
What this could lead to
If it works, this could offer a simple, low-cost way to prevent a common and serious heart rhythm complication after lung surgery.
What could go wrong
This is a phase 4 trial, but the benefit of short-term statins for this specific use is not yet proven. Statins can rarely cause muscle or liver problems.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Peking Union Medical College Hospital

    NOT_YET_RECRUITING

    Beijing, China

  • Peking Union Medical College Hospital

    RECRUITING

    Beijing, China

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