Bedside test may end guesswork in nerve pain treatment
NCT ID NCT06614322
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study aims to see if a quick bedside sensory test can predict which painkiller—pregabalin, duloxetine, or a placebo—works best for people with nerve pain in their feet. About 190 adults with diabetic, chemotherapy-related, or idiopathic nerve pain will try each treatment for 4 weeks. The goal is to personalize pain relief and speed up drug development.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Pregabalin and duloxetine
What this could lead to
If successful, this could help doctors quickly match nerve pain patients to the most effective drug, reducing trial-and-error.
What could go wrong
This is a mid-stage study with only 190 people, so results may not apply to everyone. The sensory test might not reliably predict responses.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Beth Israel Deaconess Medical Center for Autonomic and Peripheral Nerve Disorders
RECRUITINGBoston, Massachusetts, 02215, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Ichan School of Medicine at Mount Sinai
NOT_YET_RECRUITINGNew York, New York, 10029, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Pittsburgh
NOT_YET_RECRUITINGPittsburgh, Pennsylvania, 15206, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Rochester
RECRUITINGRochester, New York, 14618, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Utah
NOT_YET_RECRUITINGSalt Lake City, Utah, 84132, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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University of Vermont
RECRUITINGBurlington, Vermont, 05401, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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VCU Medical Center
NOT_YET_RECRUITINGRichmond, Virginia, 23298, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••