New therapy aims to ease trauma in ovarian cancer patients

NCT ID NCT07286162

Not yet recruiting Symptom relief Sponsor: University Health Network, Toronto Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This phase III trial tests a therapy called CALM-TF for women with advanced ovarian cancer who experience traumatic stress. 300 participants will either receive 3-6 sessions of this trauma-focused therapy or standard care. Researchers will measure stress, depression, and quality of life over 6 months to see if the therapy helps.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Trauma-Focused Managing Cancer and Living Meaningfully (CALM-TF) psychotherapy
What this could lead to: If it works, this could provide an effective therapy to reduce traumatic stress and improve quality of life for women with advanced ovarian cancer.
What could go wrong: This is a behavioral intervention, not a drug, so effects may be modest. The trial is not yet recruiting, and results depend on patient engagement and therapist skill.

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Conditions

The condition(s) this trial relates to.

ovarian cancer Recurrence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OVARIAN CANCER (OVCA) RECURRENT OVARIAN CANCER

Contacts and locations

Locations

Princess Margaret Cancer Centre

Toronto, Ontario, Canada

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