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New combo shot helps east asians shed pounds in major trial

NCT ID NCT05813925

Completed Disease control Sponsor: Novo Nordisk A/S Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a new medicine called CagriSema (a mix of two drugs) in 331 East Asian adults with obesity or overweight. Participants received a weekly injection for about 1.5 years. The main goal was to see how much weight they lost compared to another drug. The study is complete and may offer a new option for weight management.

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder Overweight type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OBESITY OR OVERWEIGHT

Contacts and locations

Locations

  • Akaicho Clinic

    Chiba-shi, Chiba, 260-0804, Japan

  • Fukuwa Clinic

    Tokyo, 104-0031, Japan

  • Fukuwa Clinic_Internal Medicine

    Tokyo, 104-0031, Japan

  • Heiwadai Hospital_Internal Medicine

    Miyazaki, Miyazaki, 880-0034, Japan

  • Iwate Medical University Uchimaru Medical Center, Division of Diabetes and Metabolism and Endocrine medicine

    Numakunai, 020-8505, Japan

  • Kawada Clinic

    Gunma, 373-0036, Japan

  • Minamino Cardiovascular Hospital_Cardiovascular medicine

    Tokyo, 192-0918, Japan

  • Naka Kinen Clinic

    Ibaraki, 311-0113, Japan

  • Naka Kinen Clinic_Internal medicine

    Ibaraki, 311-0113, Japan

  • National Taiwan University Hospital_main

    Taipei, 100, Taiwan

  • OCROM Clinic_Internal medicine

    Suita-shi, Osaka, 565-0853, Japan

  • Okabe Clinic

    Chuo-ku, Tokyo, 104-0061, Japan

  • Osaka NISHI-UMEDA Clinic

    Osaka, 530-0001, Japan

  • Osaka NISHI-UMEDA Clinic_Internal Medicine

    Osaka, 530-0001, Japan

  • Seino Internal Medicine Clinic_Internal medicine

    Koriyama-shi, Fukushima, Fukushima, Japan, 963-8851, Japan

  • Shinden Higashi Clinic

    Sendai-shi, Miyagi, 983-0039, Japan

  • Shinden Higashi Clinic_Internal medicine

    Sendai-shi, Miyagi, 983-0039, Japan

  • Shinsapporo Seiryou Hospital, General Clinical Department

    Sapporo-shi, Hokkaido, 004-0004, Japan

  • Suidoubashi Medical Clinic_Internal Medicine

    Chiyoda-ku, Tokyo, 101-0065, Japan

  • TOSAKI Clinic for Diabetes and Endocrinology_Diabetes and Endocrinology

    Aichi, 468-0009, Japan

  • The Institute of Medical Science, Asahi Life Foundation

    Chuo-ku, Tokyo, 103-0002, Japan

  • The Institute of Medical Science, Asahi Life Foundation_Internal Medicine

    Chuo-ku, Tokyo, 103-0002, Japan

  • The University of Tokyo Hospital, Diabetes and Metabolic

    Bunkyo-ku, Tokyo, 113-8655, Japan

  • ToCROM Clinic_Internal Medicine

    Tokyo, 160-0008, Japan

  • Tokyo-Eki Center-building Clinic_Internal Medicine

    Tokyo, 103-0027, Japan

  • Tsuruma Kaneshiro Diabetes Clinic

    Yamato-shi, Kanagawa, 242-0004, Japan

  • Tsuruma Kaneshiro Diabetes Clinic_Internal medicine

    Yamato-shi, Kanagawa, 242-0004, Japan

  • Yao Tokushukai General Hospital_Cardiovascular division

    Yao-shi, Osaka, 581-0011, Japan

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