New weekly shot shows promise for weight loss and diabetes

NCT ID NCT05394519

Summary

This study tested a new weekly injection called CagriSema to see if it helps people with obesity and type 2 diabetes lose weight and better control their blood sugar. About 1,200 participants were randomly assigned to receive either the real medicine or a placebo (dummy medicine) for about a year and a half. The main goals were to measure changes in body weight and see how many people achieved significant weight loss.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • AMC Community Endocrinology

    Albany, New York, 12203, United States

  • AdventHealth Diab Inst

    Orlando, Florida, 32804, United States

  • Albany House Medical Centre

    Wellingborough, NN8 4RW, United Kingdom

  • All India Institute of Medical Sciences_Delhi

    Ansārinagar, New Delhi, 110029, India

  • AmBeNet GmbH

    Leipzig, 04107, Germany

  • Amarillo Med Spec LLP

    Amarillo, Texas, 79106, United States

  • Amherst Family Practice P.C.

    Winchester, Virginia, 22601, United States

  • Antrim Area Hospital

    Antrim, BT42 2RL, United Kingdom

  • Apollo Multispeciality Hospital, Kolkata

    Kolkata, West Bengal, 700054, India

  • Apollo Multispeciality Hospitals Limited

    Kolkata, West Bengal, 700054, India

  • Apollo Research & Innovation (ARI)

    Chennai, Tamil Nadu, 600006, India

  • Ashfields Primary Care Centre

    Sandbach, CW11 1EQ, United Kingdom

  • BYL Nair Hospital and T N Medical College Department of endo

    Mumbai, Maharashtra, 400008, India

  • Bajcsy-Zsilinszky Kórház

    Budapest, 1106, Hungary

  • Barmh. Brüder Linz, Konventspital

    Linz, 4021, Austria

  • Beata Miklaszewicz & Dariusz Dabrowski "CARDIAMED" s.j.

    Legnica, Lower Silesian Voivodeship, 59-220, Poland

  • C-endo Diab Endo Clin Calgery

    Calgary, Alberta, T2V 4J2, Canada

  • CRF - Galway

    Galway, Connaght, H91 YR71, Ireland

  • CRF HRB - Galway

    Galway, Connaght, H91 YR71, Ireland

  • Calicut Medical College

    Kozhikode, Kerala, 673008, India

  • Capital Clin Res Ctr,LLC

    Olympia, Washington, 98502, United States

  • Cedar-Crosse Research Center

    Chicago, Illinois, 60607, United States

  • Centre Medical Acadie

    Montreal, Quebec, H4N 2W2, Canada

  • Centricity Res Pointe-Claire

    Pointe-Claire, Quebec, H9R 4S3, Canada

  • Centricity Research Etobicoke Endocrinology

    Etobicoke, Ontario, M9R 4E1, Canada

  • Centrum Medyczne Salvia

    Katowice, Slaskie Voivodeship, 40-772, Poland

  • Centrum Zdrowia Metabolicznego

    Poznan, Wielkopolskie Voivodeship, 60-589, Poland

  • Chrysalis Clinical Research

    St. George, Utah, 84790, United States

  • Clifton Medical Centre

    Rotherham, S65 1DA, United Kingdom

  • Clinexpert Egészségügyi Szolgáltató és Kereskedelmi Kft.

    Budapest, 1033, Hungary

  • Clinical Res Of W Florida Inc

    Clearwater, Florida, 33765, United States

  • Clinical Research Centre, St. Vincent's University Hospital,

    Dublin, Leinster, D04 T6F4, Ireland

  • Clinical Trials Research

    Lincoln, California, 95648, United States

  • Commonwealth Medical Clinic

    Mount Pearl, Newfoundland and Labrador, A1N 1W7, Canada

  • Connolly Hospital

    Dublin, Leinster, DUBLIN 15, Ireland

  • Connolly Hospital_Blanchardstown_Diabetes Day Centre

    Dublin, Leinster, D15 X40D, Ireland

  • Consano Clinical Research, LLC

    Shavano Park, Texas, 78231, United States

  • Cotton-Oneill Diabetes and End

    Topeka, Kansas, 66606-2806, United States

  • Crouch Oak Family Practice

    Addlestone, Surrey, KT15 2BH, United Kingdom

  • DCOL Ctr for Clin Res

    Longview, Texas, 75605, United States

  • Debreceni Egyetem Belgyógyászati Klinika

    Debrecen, Hajdú-Bihar, 4032, Hungary

  • Desert Oasis Hlthcr Med Group

    Palm Springs, California, 92262, United States

  • Diabetes Heart Research Centre

    Toronto, Ontario, M6G 1M2, Canada

  • Diabetes/Lipid Mgmt & Res Ctr

    Huntington Beach, California, 92648, United States

  • Diabetespraxis Mergentheim

    Bad Mergentheim, 97980, Germany

  • Diablo Clinical Research, Inc.

    Walnut Creek, California, 94598, United States

  • Dr. Harpreet Bajaj

    Brampton, Ontario, L6S 0C6, Canada

  • Dr. M.B. Jones Inc

    Victoria, British Columbia, V8V 4A1, Canada

  • East West Med Res Inst

    Honolulu, Hawaii, 96814, United States

  • Endo Res Solutions Inc

    Roswell, Georgia, 30076, United States

  • Excel Endocrine Centre

    Kolhāpur, Maharashtra, 416008, India

  • Fließer-Görzer [Ordination]

    Saint Stefan, 8511, Austria

  • Florida Institute for Clinical Research, LLC

    Orlando, Florida, 32825, United States

  • Gabinet Leczenia Otylosci i Chorob Dietozaleznych

    Bialystok, Podlaskie Voivodeship, 15-281, Poland

  • Gierach-Med

    Bygdoszcz, Kuyavian-Pomeranian Voivodeship, 85-796, Poland

  • Gierach-Med

    Bygdoszcz, 85-796, Poland

  • Gleneagles Hospitals

    Hyderabad, Telangana, 500004, India

  • Great Lakes Medical Research

    Westfield, New York, 14787, United States

  • HCG Hospitals

    Ahmedabad, Gujarat, 380006, India

  • HMC Health - Heston

    Hounslow, TW5 9ER, United Kingdom

  • Harrogate District Hospital

    Harrogate, North Yorkshire, HG2 7SX, United Kingdom

  • Hathaway Medical Centre

    Chippenham, SN14 6GT, United Kingdom

  • Headlands Research California, LLC

    Escondido, California, 92025, United States

  • Hetényi Géza Kórház

    Szolnok, Jász-Nagykun-Szolnok, 5000, Hungary

  • Hetényi Géza Kórház

    Szolnok, 5004, Hungary

  • Hillcrest Clinical Research

    Simpsonville, South Carolina, 29681-1538, United States

  • Holston Medical Group

    Kingsport, Tennessee, 37660, United States

  • Hospital Ampang

    Ampang, Selangor, Selangor, 68000, Malaysia

  • Hospital Canselor Tuanku Muhriz UKM

    Cheras, Kuala Lumpur, 56000, Malaysia

  • Hospital Melaka

    Malacca, 75400, Malaysia

  • Hospital Miri

    Miri, Sarawak, 98000, Malaysia

  • Hospital Putrajaya

    Putrajaya, Putrajaya, 62250, Malaysia

  • Hospital Seri Manjung

    Seri Manjung, Perak, 32040, Malaysia

  • Hospital Tuanku Jaafar

    Seremban, 70300, Malaysia

  • Hospital Universiti Sains Malaysia

    Kota Bharu, Kelantan, 16150, Malaysia

  • Imed 19- privat

    Vienna, 1190, Austria

  • Indian Institute of Diabetes

    Thiruvnanthapuram, Kerala, 695033, India

  • InnoDiab Forschung GmbH

    Essen, 45136, Germany

  • Institut für Diabetesforschung GmbH Münster - Dr. med. Rose

    Münster, 48145, Germany

  • Instytut Diabetologii Sp. z o.o.

    Warsaw, Mazovian Voivodeship, 02-117, Poland

  • Instytut Diabetologii Sp. z o.o.

    Warsaw, Mazovian, 02-117, Poland

  • International Diabetes Center

    Minneapolis, Minnesota, 55416, United States

  • Iowa Diab & Endo Res Center

    West Des Moines, Iowa, 50266, United States

  • J K Lon Hospital, SMS Medical College & Attached Hospitals

    Jaipur, Rajasthan, 302004, India

  • Jacksonville Ctr For Clin Res

    Jacksonville, Florida, 32216, United States

  • John Muir Physicians Network

    Concord, California, 94520, United States

  • Joint Clinical Research Facility - Swansea

    Swansea, SA2 8PP, United Kingdom

  • Kiltearn Medical Centre

    Nantwich, CW5 5NX, United Kingdom

  • King Chulalongkorn Memorial Hospital_Bangkok

    Bangkok, 10330, Thailand

  • King Chulalongkorn Memorial Hospital_Endocrinology

    Bangkok, 10330, Thailand

  • Klinik Landstraße

    Vienna, 1030, Austria

  • Klinika Bellamed

    Elblag, Warmian-Masurian Voivodeship, 82-300, Poland

  • Komáromi Selye János Kórház

    Komárom, Komárom-Esztergom, 2900, Hungary

  • L-MARC Research Center

    Louisville, Kentucky, 40213, United States

  • LMC Clin Res Inc. Calgary

    Calgary, Alberta, T2H 2G4, Canada

  • LMC Clin Rsrch Inc. (Montreal)

    Saint-Laurent, Quebec, H4T 1Z9, Canada

  • LMC Research Inc. Ottawa

    Nepean, Ontario, K2J 0V2, Canada

  • Lady Hardinge Medical College

    New Delhi, 110001, India

  • Layton Medical Centre

    Blackpool, FY3 7EN, United Kingdom

  • Leicester General Hospital

    Leicester, LE5 4PW, United Kingdom

  • Linden sp. z o.o. sp. k.

    Krakow, Lesser Poland Voivodeship, 30-721, Poland

  • Linden sp. z o.o. sp. k.

    Krakow, 30-721, Poland

  • MZM Praxis Drs. Erlinger

    Stuttgart, 70378, Germany

  • Madras Diabetes Research Foundation

    Chennai, Tamil Nadu, 600086, India

  • Mater Miscericordiae Hospital

    Dublin, Leinster, D07 XAO9, Ireland

  • Mater Miscericordiae Hospital

    Dublin, Leinster, DUBLIN 7, Ireland

  • Medical Concierge Centrum Medyczne

    Warsaw, Masovian Voivodeship, 02-798, Poland

  • Mercury Str Med Grp, PLLC

    Butte, Montana, 59701, United States

  • Milestone Research

    London, Ontario, N5W 6A2, Canada

  • Musgrove Park Hospital

    Taunton, TA1 5DA, United Kingdom

  • Naka Kinen Clinic_Internal medicine

    Ibaraki, 311-0113, Japan

  • National Clin Res Inc.

    Richmond, Virginia, 23294, United States

  • New West Physicians,Inc.

    Golden, Colorado, 80401, United States

  • Noble Hospitals Pvt Ltd.

    Pune, Maharashtra, 411013, India

  • North Texas Endocrine Center

    Dallas, Texas, 75231, United States

  • Northeast Research Institute

    Fleming Island, Florida, 32003, United States

  • Northern Pines Hlth Ctr, PC

    Buckley, Michigan, 49620, United States

  • Osaka Nishiumeda Clinic_Diabetes Internal Medicine

    Osaka, 530-0001, Japan

  • Osaka University Hospital_Metabolic Medicine

    Osaka, 565-0871, Japan

  • Oviedo Medical Research, LLC

    Oviedo, Florida, 32765, United States

  • Pennington Biom Res Ctr

    Baton Rouge, Louisiana, 70808, United States

  • PharmQuest Life Sciences LLC

    Greensboro, North Carolina, 27408, United States

  • PlanIt Research, PLLC

    Houston, Texas, 77079, United States

  • Ponce Med School Found Inc

    Ponce, 00716, Puerto Rico

  • Post Graduate Institute of Medical Education & Research_Chandigarh

    Chandigarh, Punjab, 160012, India

  • Providence Medical Foundation

    Fullerton, California, 92835, United States

  • Rajavithi Hospital

    Bangkok, 10400, Thailand

  • Rajavithi Hospital_Diabetes and Endocrinology

    Bangkok, 10400, Thailand

  • Ramaiah Memorial Hospital

    Bangalore, Karnataka, 560054, India

  • Ramathibodi Hospital

    Bangkok, Ratchathewi Bangkok, 10400, Thailand

  • Ramathibodi Hospital

    Bangkok, 10400, Thailand

  • Renstar Medical Research

    Ocala, Florida, 34470, United States

  • Royal Cornwall Hospital (Treliske)

    Truro, TR1 3LJ, United Kingdom

  • SMS Medical College & Hospital

    Jaipur, Rajasthan, 302004, India

  • Samodzielny Publiczny Szpital Kliniczny Im. Prof. W. Orłowskiego Centrum Medycznego Kształcenia Podyplomowego

    Warsaw, Masovian Voivodeship, 00-416, Poland

  • Sarawak General Hospital

    Kuching, Sarawak, 93586, Malaysia

  • Selma Medical Associates

    Winchester, Virginia, 22601-3834, United States

  • Selye János Kórház és Rendelőintézet

    Komárom, 2900, Hungary

  • Seth GS medical college and KEM Hospital

    Mumbai, Maharashtra, 400012, India

  • Siriraj Hospital_Bangkoknoi, Bangkok

    Bangkoknoi, Bangkok, Bangkok, 10700, Thailand

  • Siriraj Hospital_Dept Endocrinology

    Bangkok, 10700, Thailand

  • Southgate Medical Group, LLP

    West Seneca, New York, 14224, United States

  • Southmead Hospital

    Bristol, BS10 5NB, United Kingdom

  • Srinagarind Hospital

    Khon Kaen, 40002, Thailand

  • St James's CRF

    Dublin, Leinster, D08 A978, Ireland

  • St. Jos Heritage Hlthcr_Fllrtn

    Fullerton, California, 92835, United States

  • Staploe Medical Centre

    Soham, CB7 5JD, United Kingdom

  • StudyMetrix Research LLC

    City of Saint Peters, Missouri, 63303, United States

  • Sunil's Diabetes Care n' Research Centre Pvt Ltd

    Nagpur, Maharashtra, 440010, India

  • Sunil's Diabetes Care n' Research Centre Pvt Ltd

    Nagpur, 440010, India

  • Szegedi Tudomanyegyetem St Györgyi Albert Klinikai Központ

    Szeged, Csongrád-Csanád, 6725, Hungary

  • Szőcs Depot Egészségügyi Szolgáltató Kft.

    Budapest, 1042, Hungary

  • TOSAKI Clinic for Diabetes and Endocrinology_Diabetes and Endocrinology

    Aichi, 468-0009, Japan

  • Takatsuki Red Cross Hospital

    Osaka, 569-1045, Japan

  • Terpa Sp. z o.o. Sp. k.

    Lublin, Lubelskie Voivodeship, 20-333, Poland

  • Terpa Sp. z o.o. Sp. k.

    Lublin, 20-333, Poland

  • Texas Diab & Endo, P.A.

    Austin, Texas, 78731, United States

  • Texas Diab & Endo, P.A.

    Austin, Texas, 78749, United States

  • Thammasat Hospital_Cardiology

    Pathum Thani, 12120, Thailand

  • The Health Centre

    Bradford-on-Avon, BA15 1DQ, United Kingdom

  • Tokuyama clinic_Diabetic internal medicine

    Chiba, 261-0004, Japan

  • Trialmed CRS

    Piotrkow Trybunalski, Łódź Voivodeship, 97-300, Poland

  • UT Southwestern Med Cntr

    Dallas, Texas, 75390-9302, United States

  • University Technology MARA (UiTM) - Sg Buloh

    Sungai Buloh, Selangor, 47000, Malaysia

  • Universitätsklinik für Innere Medizin Graz

    Graz, 8036, Austria

  • Universitätsklinikum AKH Wien

    Vienna, 1090, Austria

  • Universitätsklinikum Freiburg - Innere Medizin II

    Freiburg im Breisgau, 79106, Germany

  • Uniwersytecki Szpital Kliniczny w Bialymstoku

    Bialystok, Podlaskie Voivodeship, 15-276, Poland

  • Uniwersytecki Szpital Kliniczny w Bialymstoku

    Bialystok, 15-276, Poland

  • Uniwersyteckie Centrum Kliniczne

    Gdansk, Pomeranian Voivodeship, 80-214, Poland

  • Uniwersyteckie Centrum Kliniczne

    Gdansk, 80-952, Poland

  • Velocity Clin Res Los Angeles

    Los Angeles, California, 90017, United States

  • Velocity Clin Res Wstlke

    Los Angeles, California, 90057, United States

  • Velocity Clinical Res-Dallas

    Dallas, Texas, 75230, United States

  • Wendisch - Dahl Hamburg - DZHW

    Hamburg, 22607, Germany

  • Wharton Med Clin Trials

    Hamilton, Ontario, L8L 5G8, Canada

  • Zentrum fuer klinische Studien Suedbrandenburg GmbH

    Elsterwerda, 04910, Germany

  • Zentrum für klinische Studien Alexander Segner

    Saint Ingbert-Oberwürzbach, 66386, Germany

  • Zentrum für klinische Studien Allgäu Oberschwaben

    Wangen, 88239, Germany

Conditions

Explore the condition pages connected to this study.