Heart surgery showdown: which procedure saves more lives?

NCT ID NCT05427370

Recruiting now Disease control Sponsor: Sunnybrook Health Sciences Centre Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two common heart procedures—bypass surgery (CABG) and stenting (PCI)—in 754 people with severe coronary artery disease and a weak heart pump. The goal is to see which approach better prevents death, stroke, heart attacks, or repeat procedures over 5 years. Participants must have multiple blocked arteries and a heart pumping ability of 40% or less.

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Conditions

The condition(s) this trial relates to.

coronary artery disorder systolic heart failure Ventricular Dysfunction, Left

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CORONARY ARTERY DISEASE HEART FAILURE, SYSTOLIC

Contacts and locations

Locations

Al Nas Hospital
RECRUITING

Cairo, Qalyubia Governorate, Egypt
Cedars-Sinai
RECRUITING

Los Angeles, California, 90048, United States
Center Hospitalier Universitaire de Montreal
RECRUITING

Montreal, Quebec, , H2X OC1, Canada
Centro Hospitalar e Universitário Sao João
RECRUITING

Porto, 4200-319, Portugal
Clinical Hospital Dubrava
RECRUITING

Sušak, Zagreb, 10000, Croatia
Dedinje Cardiovascular Institute
RECRUITING

Belgrade, Serbia
European Hospital, Via Portuense
RECRUITING

Roma, RM, 00149, Italy
Fraser Health; Royal Columbian Hospital
WITHDRAWN

New Westminster, British Columbia, V3L3W7, Canada
G Kuppuswamy Naidu Memorial Hospital (GKNM)
RECRUITING

Palayam, Tamil Nadu, 641037, India
Hamilton General Hospital
RECRUITING

Hamilton, Ontario, L8L 2X2, Canada
Heart Institute, Medical School of the University of Sao Paulo_INCOR
RECRUITING

São Paulo, 05403-900, Brazil
Hospital Clinic de Barcelona (ICCV)
RECRUITING

Barcelona, L'Eixample, 08036, Spain
Hospital Clínico Universitario Virgen de la Arrixaca
RECRUITING

El Palmar, Murcia, 30120, Spain
Hospital Sacre-Coeur
RECRUITING

Montreal, Quebec, H4J 1C5, Canada
Hospital Universitario de Navarra
RECRUITING

Pamplona, 31008, Spain
Hospital del Vinalopó
RECRUITING

Alicante, Spain
Institut de Cardiologie Quebec (QC) - Laval
RECRUITING

Québec, Quebec, G1V 4G5, Canada
Instituto Mexicano del Seguro Social (IMSS)
RECRUITING

Mexico City, Mexico
Jilin Heart Hospital
RECRUITING

Jilin City, Changchun, 130117, China
John Hopkins Hospital
RECRUITING

Baltimore, Maryland, 21205, United States
Leipzig Heart Center
RECRUITING

Leipzig, 04289, Germany
London Health Sciences Center, University Hospital
RECRUITING

London, Ontario, N6A 5A5, Canada
Mackenzie Health Sciences Center
RECRUITING

Edmonton, Alberta, T6G 2B7, Canada
Mayo Clinic
WITHDRAWN

Rochester, Minnesota, 55905, United States
Medical University Bialystok
RECRUITING

Bialystok, 15-089, Poland
Medical University of Silesia
ACTIVE_NOT_RECRUITING

Katowice, Poland
Medical University of Vienna
ACTIVE_NOT_RECRUITING

Vienna, Austria
Montreal Heart Institute
RECRUITING

Montreal, Quebec, H1T 1C8, Canada
Ottawa Heart Institute
RECRUITING

Ottawa, Ontario, K1Y 4W7, Canada
Providence Health
RECRUITING

Vancouver, British Columbia, V6Z 1Y6, Canada
Queen Elizabeth II Hospital
RECRUITING

Halifax, Nova Scotia, B3H 2Y9, Canada
Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
RECRUITING

Shanghai, 200031, China
Southlake Regional HC
RECRUITING

Newmarket, Ontario, L3Y 2P9, Canada
St. Michael's
RECRUITING

Toronto, Ontario, M5B 1W8, Canada
Sunnybrook Health Sciences Center
RECRUITING

Toronto, Ontario, M4N 3M5, Canada
The University of Manitoba and St. Boniface Hospital Inc.
RECRUITING

Winnipeg, Manitoba, R2H 2A6, Canada
Toronto General Hospital
RECRUITING

Toronto, Ontario, M5G 2N2, Canada
Unidade Local de Saude Lisboa Ocidental (ULSLO)
RECRUITING

Lisbon, 1350-410, Portugal
University Hospital Dusseldorf
RECRUITING

Düsseldorf, 40225, Germany
University Hospitals Cleveland Medical Center
RECRUITING

Cleveland, Ohio, 44106, United States
University of Calgary; Libin Cardiovascular Institute
RECRUITING

Calgary, Alberta, T2N 4Z6, Canada
UofL Health, Inc
RECRUITING

Louisville, Kentucky, 40202, United States
Yale University
RECRUITING

New Haven, Connecticut, 06510, United States

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