New hope for young minds: depression drug trial for children
NCT ID NCT02129751
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study tests whether bupropion hydrobromide (Aplenzin) can safely ease depression symptoms in children and adolescents aged 7 to 17. About 246 participants will receive either the drug or a placebo. The main goal is to see if depression scores improve by the end of treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
bupropion hydrobromide (Aplenzin)
What this could lead to
If successful, this could provide a new treatment option for depression in children and adolescents.
What could go wrong
This is a Phase 4 trial, but results may not apply to all ages or severities. Side effects like seizures or mood changes are possible.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••