New drug buntanetap tested for Long-Term safety in Parkinson's patients

NCT ID NCT07284784

Recruiting now Disease control Sponsor: Annovis Bio Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 22, 2026 · Updated 2 times

Summary

This study is testing the long-term safety of a daily drug called buntanetap in 500 people with Parkinson's disease over 36 months. It includes two groups: those who have taken buntanetap before and those who have a deep brain stimulation device. The main goal is to see if the drug is safe and what side effects may occur.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: buntanetap (a drug taken as a daily capsule)
What this could lead to: If successful, this could show that buntanetap is safe for long-term use in Parkinson's disease, potentially offering a new treatment option to slow progression.
What could go wrong: This is an early-to-mid-stage trial focused on safety, not yet proving effectiveness. Side effects or lack of benefit may emerge, and results may not apply to all Parkinson's patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DEEP BRAIN STIMULATION PARKINSON'S DISEASE (PD)

Contacts and locations

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Locations

Abington Neurology
RECRUITING

Willow Grove, Pennsylvania, 19090, United States
Accel Clinical Sites-Georgia LLC dba Accel Research Sites-Lake Oconee CRU
RECRUITING

DeLand, Florida, 32720, United States
Arrow Clinical Trials
RECRUITING

Daytona Beach, Florida, 32117, United States
Banner Sun Health Research Institute - Cleo Roberts Center for Clinical Research
RECRUITING

Sun City, Arizona, 85351, United States
Cenexel Rocky Mountain Clinical Research
RECRUITING

Englewood, Colorado, 80113, United States
Central Texas Neurology
RECRUITING

Round Rock, Texas, 78681, United States
Conquest Research
RECRUITING

Winter Park, Florida, 32789, United States
Duke Department of Neurosurgery
RECRUITING

Durham, North Carolina, 27710, United States
First Choice Neurology - Aventura Neurologic Associates
RECRUITING

Aventura, Florida, 33180, United States
Inland Northwest Research
RECRUITING

Spokane, Washington, 99202, United States
Josephson Wallack Munshower Neurology, P.C.
RECRUITING

Indianapolis, Indiana, 46256, United States
Medical College of Wisconsin
RECRUITING

Milwaukee, Wisconsin, 53226, United States
Medical University of South Carolina (MUSC) - The Murray Center for Research on Parkinson's Disease
NOT_YET_RECRUITING

Charleston, South Carolina, 29401, United States
Mount Sinai Hospital
RECRUITING

New York, New York, 10019, United States
Neurology Clinic, P.C.
RECRUITING

Cordova, Tennessee, 38018, United States
New England Institute for Clinical Research (Ki Health Partners)
RECRUITING

Stamford, Connecticut, 06824, United States
Parkinson's & Movement Disorder Institute (PMDI) - Orange County Office
RECRUITING

Fountain Valley, California, 92708, United States
Quest Research Institute
RECRUITING

Farmington Hills, Michigan, 48334, United States
Renstar Medical Research
RECRUITING

Ocala, Florida, 34470, United States
The Movement Disorder Clinic of Oklahoma
RECRUITING

Tulsa, Oklahoma, 74136, United States

Contact Email: •••••@•••••
The Ohio State University Wexner Medical Center
RECRUITING

Columbus, Ohio, 43210, United States
University of Alabama at Birmingham
RECRUITING

Birmingham, Alabama, 35233, United States
University of Kansas Medical Center (KUMC) - School of Medicine - Parkinson's Disease and Movement D
RECRUITING

Kansas City, Kansas, 66160, United States
University of South Florida (USF) - University of South Florida College of Medicine - Parkinson's Di
RECRUITING

Tampa, Florida, 33613, United States
University of Virginia Health System (UVAHS) - Adult Neurology Clinic
RECRUITING

Charlottesville, Virginia, 22903, United States
Veracity Neuroscience LLC
RECRUITING

Memphis, Tennessee, 38157, United States
iResearch Atlanta
RECRUITING

Decatur, Georgia, 30030, United States

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