Budesonide pill may shield myeloma patients from brutal transplant diarrhea
NCT ID NCT05405387
First seen Nov 21, 2025 · Last updated Jun 22, 2026 · Updated 21 times
Summary
This phase 2 trial tests whether the drug budesonide can prevent severe diarrhea in multiple myeloma patients receiving a stem cell transplant. About 120 adults will take either budesonide or a placebo for two weeks starting just before their transplant. The goal is to see if the drug reduces diarrhea and other complications, making recovery smoother.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Huntsman Cancer Institute at the University of Utah
RECRUITINGSalt Lake City, Utah, 84112, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Budesonide (Entocort EC)
What this could lead to
If it works, this could give doctors a simple way to prevent severe diarrhea during stem cell transplant for multiple myeloma, making the procedure easier to tolerate.
What could go wrong
This is a small, early-phase trial (120 people) testing a drug already used for other conditions. It may not reduce diarrhea significantly, and side effects from budesonide are possible.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.