Experimental cancer injection shows promise but trial ends early

NCT ID NCT04725331

First seen Nov 21, 2025 · Last updated May 24, 2026 · Updated 20 times

Summary

This study tested an experimental drug called BT-001, injected directly into tumors, either alone or with the immunotherapy pembrolizumab, in people with advanced solid tumors (like melanoma, lung, or breast cancer). The goal was to see if it was safe and could shrink tumors. The trial was stopped early, but data from 31 participants helps researchers understand safety and immune response.

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Contacts and locations

Locations

  • Centre Léon Bérard

    Lyon, 69008, France

  • Clinique Universitaire Saint-Luc

    Brussels, 1200, Belgium

  • Hôpital Saint-Louis AP-HP

    Paris, 75010, France

  • Institut Bergonié

    Bordeaux, 33000, France

  • Institut Gustave Roussy

    Villejuif, 94800, France

Conditions

Explore the condition pages connected to this study.