Scientists track lung bacteria for 3 years to predict bronchiectasis Flare-Ups

NCT ID NCT04966793

Recruiting now Knowledge-focused Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study follows 1,850 bronchiectasis patients over three years, collecting sputum samples monthly to analyze how lung bacteria change over time. Researchers will sequence the DNA of bacteria like Pseudomonas aeruginosa to see how they evolve and become resistant to antibiotics. The goal is to better predict acute attacks and find new ways to prevent infections by adjusting the lung microbiome.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help doctors predict flare-ups and find new ways to prevent infections by adjusting lung bacteria.
What could go wrong: This is an observational study, not a treatment trial. It will not directly improve health, and results may take years to apply.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

bronchiectasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BRONCHIECTASIS

Contacts and locations

Locations

2ndAffiliated Hospital, School of Medicine, Zhejiang University
RECRUITING

Hangzhou, Zhejiang, China

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