New drug aims to cut dangerous lung Flare-Ups in chronic disease

NCT ID NCT07201051

Recruiting now Disease control Sponsor: GlaxoSmithKline Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 13, 2026 · Updated 5 times

Summary

This study tests a new drug called GSK3862995B in 446 adults with bronchiectasis, a long-term lung condition. The goal is to see if the drug can reduce the number of serious lung infections (exacerbations) compared to a placebo. Participants will receive either one of two doses of the drug or a placebo, and researchers will also check safety and how the body handles the drug.

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Conditions

The condition(s) this trial relates to.

bronchiectasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BRONCHIECTASIS

Contacts and locations

Locations

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Mobile, Alabama, 36608, United States
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Phoenix, Arizona, 85027, United States
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La Palma, California, 90623, United States
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Valencia, California, 91355, United States
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Aurora, Colorado, 80012, United States
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Miami, Florida, 33126, United States
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Miami, Florida, 33176, United States
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Naples, Florida, 34102, United States
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Pembroke Pines, Florida, 33029, United States
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Plantation, Florida, 33324, United States
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St. Petersburg, Florida, 33707, United States
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Tamarac, Florida, 33321, United States
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Winter Park, Florida, 32789, United States
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Hammond, Indiana, 46324, United States
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New Orleans, Louisiana, 70112, United States
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Rockville, Maryland, 20854, United States
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St Louis, Missouri, 63110, United States
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Henderson, Nevada, 89052, United States
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New Hyde Park, New York, 11040, United States
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Winston-Salem, North Carolina, 27103, United States
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DuBois, Pennsylvania, 15801, United States
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Anderson, South Carolina, 29621, United States
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Rock Hill, South Carolina, 29732, United States
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Spartanburg, South Carolina, 29303, United States
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Union, South Carolina, 29379, United States
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Franklin, Tennessee, 37067, United States
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Knoxville, Tennessee, 37919, United States
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Conroe, Texas, 77384, United States
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Cypress, Texas, 77429, United States
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Sugar Land, Texas, 77479, United States
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Williamsburg, Virginia, 23188, United States
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Buenos Aires, C1128AAF, Argentina
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CABA, C1023AAB, Argentina
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CABA, C1426ABP, Argentina
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Rosario Provincia de Santa FE, S2000DEJ, Argentina
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San Miguel de Tucumán, T4000IAI, Argentina
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San Miguel de Tucumán, T4000IFL, Argentina
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San Miguel de Tucumán, T4000IHE, Argentina
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Santa Fe, S3000ASF, Argentina
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Beijing, 100020, China
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Chongqing, 408099, China
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Dongguan, 523326, China
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Guangzhou, 510180, China
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Guangzhou, 510230, China
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Guilin, 541002, China
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Hangzhou, 310000, China
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Huizhou, 516000, China
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Jiangmen, 529700, China
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Jiangsu, 221004, China
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Nanjing, 210012, China
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Qingyuan, 511500, China
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Shanghai, China
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Taizhou, 317000, China
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Weifang, China
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Yangzhou, 225001, China
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Zhanjiang, 524001, China
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Bendorf, 56170, Germany
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Berlin, 12203, Germany
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Frankfurt, 60389, Germany
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Frankfurt, 60596, Germany
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Geesthacht, 21502, Germany
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Hamburg, 22767, Germany
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München, 81241, Germany
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Ashdod, 7747629, Israel
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Ashkelon, 78278, Israel
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Beersheba, 84101, Israel
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Haifa, 3436212, Israel
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Jerusalem, 91031, Israel
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Jerusalem, 91120, Israel
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Kfar Saba, 44281, Israel
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Koranit, 2018100, Israel
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Petah Tikva, 49100, Israel
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Tel Aviv, 64239, Israel
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Milan, 20122, Italy
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Naples, 80131, Italy
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Roma, 11166, Italy
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Toyonaka-Shi, Osaka, 560-0045, Japan
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Aichi, 465-8620, Japan
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Aichi, 466-8560, Japan
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Fukuoka, 811-3195, Japan
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Fukuoka, 812-0054, Japan
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Fukuoka, 814-0180, Japan
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Fukuoka, 820-8505, Japan
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Hyōgo, 650-0047, Japan
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Ibaraki, 311-3193, Japan
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Ibaraki, 319-1113, Japan
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Ishikawa, 920-8650, Japan
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Kanagawa, 234-8503, Japan
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Kanagawa, 247-8533, Japan
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Mie, 515-8544, Japan
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Miyagi, 980-0873, Japan
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Osaka, 530-8480, Japan
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Tokyo, 162-8655, Japan
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Tokyo, 204-8522, Japan
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Tokyo, 204-8585, Japan
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Auckland, 1051, New Zealand
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Kapiti, 5036, New Zealand
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Bialystok, 15-044, Poland
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Ksawerów, 95-054, Poland
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Piaseczno, 05-500, Poland
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Rzeszów, 35-051, Poland
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Sosnowiec, 41-208, Poland
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Busan, 48108, South Korea
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Incheon, 21565, South Korea
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Incheon, 22332, South Korea
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Jeonju, 54907, South Korea
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Seoul, 03312, South Korea
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Seoul, 04763, South Korea
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Seoul, 06273, South Korea
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Seoul, 08308, South Korea
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Seoul, 7061, South Korea
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Barcelona, 08003, Spain
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Barcelona, 08035, Spain
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Barcelona, 08036, Spain
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Lleida, 25198, Spain
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Madrid, 28003, Spain
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Madrid, 28040, Spain
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Madrid, 28041, Spain
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Madrid, 28223, Spain
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MErida Badajoz, 06800, Spain
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Oviedo, 33011, Spain
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Valencia, 46015, Spain
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North Finchley, London, N3 2JU, United Kingdom
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Bedford, MK40 2FG, United Kingdom
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Bristol Avon, BS10 5NB, United Kingdom
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Coventry, CV2 2DX, United Kingdom
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Dagenham, RM9 5NH, United Kingdom
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Dundee, DD1 9SY, United Kingdom
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High Wycombe, HP11 2QW, United Kingdom
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Little Baldon, OX44 9PU, United Kingdom
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Liverpool, L14 3PE, United Kingdom
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London, N8 0RA, United Kingdom
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Sheffield, S5 7AU, United Kingdom
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Tyne and Wear, NE29 8NH, United Kingdom

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