New drug aims to improve schizophrenia treatment and reduce relapse

NCT ID NCT07410507

Recruiting now Disease control Sponsor: Eli Lilly and Company Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 07, 2026 · Updated 6 times

Summary

This study tests whether adding brenipatide to standard schizophrenia medication is safe and effective. About 450 adults with schizophrenia will receive either brenipatide or a placebo for up to 12 months. The study looks at weight changes, cognitive function, and time to relapse.

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Conditions

The condition(s) this trial relates to.

schizophrenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SCHIZOPHRENIA

Contacts and locations

Locations

Accel Research Sites - Maitland Clinical Research Unit
RECRUITING

Maitland, Florida, 32751, United States
Adams Clinical Dallas
RECRUITING

DeSoto, Texas, 75115, United States
Adams Clinical Harlem
RECRUITING

New York, New York, 10029, United States
Adams Clinical Philadelphia
RECRUITING

Philadelphia, Pennsylvania, 19104, United States
Adams Clinical Watertown
RECRUITING

Watertown, Massachusetts, 02472, United States
All India Institute of Medical Sciences (AIIMS) - Bhopal
RECRUITING

Bhopal, 462024, India
Apg Research, Llc
RECRUITING

Orlando, Florida, 32803, United States
Arata Clinic
RECRUITING

Nagasaki, 852-8137, Japan
Arch Clinical Trials
RECRUITING

St Louis, Missouri, 63141, United States
Asuka Hospital
NOT_YET_RECRUITING

Machida, 194-0005, Japan
Atlanta Center for Medical Research
RECRUITING

Atlanta, Georgia, 30331, United States
Augusta University
RECRUITING

Augusta, Georgia, 30912, United States
CBH Health
RECRUITING

Gaithersburg, Maryland, 20877, United States
CEN Centro Especializado en Neurociencias
RECRUITING

Córdoba, 5000, Argentina
CLA Research
RECRUITING

Naples, Florida, 34116, United States
CPQuali Pesquisa Clínica
RECRUITING

São Paulo, 01228-000, Brazil
Calida Rehab - Karjat
NOT_YET_RECRUITING

Karjat, 410201, India
Career Institute of Medical Sciences and Hospital - Lucknow
RECRUITING

Lucknow, 226020, India
Catalina Research Institute, LLC
NOT_YET_RECRUITING

Montclair, California, 91763, United States
Centro Médico Luquez
RECRUITING

Córdoba, X5006CBI, Argentina
Centro Neurobiológico y de Estrés Traumático (CENydET)
RECRUITING

Buenos Aires, 1058, Argentina
Centro de Investigaciones Metabólicas (CINME)
NOT_YET_RECRUITING

Buenos Aires, C1056ABI, Argentina
Centro de Investigación y Asistencia en Psiquiatría (CIAP)
RECRUITING

Rosario, 2000, Argentina
Chang Gung Medical Foundation-Linkou Branch
RECRUITING

Taoyuan, 333, Taiwan
Changhua Christian Hospital
NOT_YET_RECRUITING

Changhua, 50006, Taiwan
Chronos Pesquisa Clínica
NOT_YET_RECRUITING

Brasília, 72145-450, Brazil
Chung Shan Medical University Hospital
NOT_YET_RECRUITING

Taichung, 402, Taiwan
Clinica Viver - Centro de Desospitalizacao Humana
NOT_YET_RECRUITING

São Paulo, 04020-060, Brazil
Clinical Innovations, Inc. dba CITrials
RECRUITING

Bellflower, California, 90706, United States
Clinilive
NOT_YET_RECRUITING

Maringá, 87013-250, Brazil
Collaborative Neuroscience Research, LLC
RECRUITING

Garden Grove, California, 92845, United States
Collaborative Neuroscience Research, LLC
RECRUITING

Torrance, California, 90502, United States
D.Y. Patil Hospital
RECRUITING

Navi Mumbai, 400706, India
Dharwad Institute Of Mental Health And Neurosciences
RECRUITING

Dharwad, 580008, India
Dr. Ram Manohar Lohia Institute of Medical Sciences
RECRUITING

Lucknow, 226010, India
Fujimidai Hospital
NOT_YET_RECRUITING

Hiratsuka, 259-1205, Japan
Fundacion Estudios Clinicos
RECRUITING

Rosario, 2000, Argentina
Fundación para el Estudio y Tratamiento de Enfermedades Mentales (FETEM)
RECRUITING

Buenos Aires, 1133, Argentina
Galaxy Superspeciality Hospital
RECRUITING

Aurangabad, 431001, India
Global Psy Asociación Civil
RECRUITING

La Plata, 1904, Argentina
Graphic Era Institute of Medical Sciences and Hospital
NOT_YET_RECRUITING

Dehradun, 248008, India
Himorogi Psychiatric Institute - Tokyo - Ichigayatamachi
NOT_YET_RECRUITING

Tokyo, 162-0843, Japan
Hirota Clinic
NOT_YET_RECRUITING

Kurume, 830-0033, Japan
Horikoshi Mental Somatic Clinic
NOT_YET_RECRUITING

Fukushima, 960-8053, Japan
Hospital das Clínicas da UFMG
NOT_YET_RECRUITING

Belo Horizonte, 30130-100, Brazil
INSA Instituto de Neurociencia San Agustin
NOT_YET_RECRUITING

La Plata, 1900, Argentina
Innovative Clinical Research
RECRUITING

Lauderhill, Florida, 33319, United States
Insight Clinical Trials
RECRUITING

Independence, Ohio, 44131, United States
Institute of Living
RECRUITING

Hartford, Connecticut, 06106, United States
Instituto Apice
NOT_YET_RECRUITING

Salvador, 40170-180, Brazil
Instituto Atena de Pesquisa Clinica
NOT_YET_RECRUITING

Natal, 59020-500, Brazil
Instituto Kremer
RECRUITING

Córdoba, X5004AOA, Argentina
Instituto Nacional de Psicopatología (INAPsi)- FunDaMos
RECRUITING

Buenos Aires, 1405, Argentina
Instituto de Pesquisa clinica de Campinas
NOT_YET_RECRUITING

Campinas, 13060-080, Brazil
Keelung Chang Gung Memorial Hospital
RECRUITING

Keelung, 204, Taiwan
Lifepoint Multispeciality Hospital
RECRUITING

Pune, 411057, India
Magno Medical Research Group
RECRUITING

Cooper City, Florida, 33024, United States
McLean Hospital
RECRUITING

Belmont, Massachusetts, 02478, United States
Medipoint Hospitals Pvt. Ltd.
RECRUITING

Pune, 411007, India
National Center of Neurology and Psychiatry
NOT_YET_RECRUITING

Kodaira, 187-8551, Japan
National Cheng Kung University Hospital
NOT_YET_RECRUITING

Tainan, 704, Taiwan
National Taiwan University Hospital
RECRUITING

Taipei, 10002, Taiwan
NextPhase Research Florida - Hollywood
NOT_YET_RECRUITING

Hollywood, Florida, 33024, United States
Northwest Clinical Research Center
RECRUITING

Bellevue, Washington, 98007, United States
Okehazama Hospital
NOT_YET_RECRUITING

Toyoake, 470-1168, Japan
PSEG Centro de Pesquisa Clínica
NOT_YET_RECRUITING

São Paulo, 04038-002, Brazil
Pillar Clinical Research- Little Rock
RECRUITING

Little Rock, Arkansas, 72204, United States
Rainbow and Sea Hospital
NOT_YET_RECRUITING

Karatsu, 847-0031, Japan
Rajiv Gandhi Government General Hospital
NOT_YET_RECRUITING

Chennai, 600003, India
Re:Cognition Health - Chicago
RECRUITING

Chicago, Illinois, 60611, United States
Re:Cognition Health - Fort Worth
RECRUITING

Fort Worth, Texas, 76104, United States
Resolution Psychopharmacology Research Institute
RECRUITING

Mendoza, 5502, Argentina
Ruschel Medicina e Pesquisa Clínica
NOT_YET_RECRUITING

Rio de Janeiro, 22270-060, Brazil
Sanatorio Morra S.A.
NOT_YET_RECRUITING

Córdoba, 5000, Argentina
Seinan Hospital
NOT_YET_RECRUITING

Hachinohe, 039-1104, Japan
Shioiri Mental Clinic
NOT_YET_RECRUITING

Yokosuka, 238-0042, Japan
Sho Midori Hospital
NOT_YET_RECRUITING

Saitama, 336-0022, Japan
Shree Mahalaxmi DIATONE Institute
NOT_YET_RECRUITING

Kolhāpur, 416001, India
Sowmanasya Hospital and Institute of Psychiatry
RECRUITING

Tiruchirappalli, 620002, India
Stanford University School of Medicine
RECRUITING

Stanford, California, 94305, United States
Sunwise Clinical Research
RECRUITING

Walnut Creek, California, 94596, United States
Suzhou Guangji Hospital
RECRUITING

Suzhou, 215003, China
Taipei City Hospital - Songde Branch
NOT_YET_RECRUITING

Taipei, 110204, Taiwan
Taipei Medical University Hospital
RECRUITING

Taipei, 110, Taiwan
Taipei Veterans General Hospital
RECRUITING

Taipei, 11217, Taiwan
The Fourth People's Hospital of Chengdu
RECRUITING

Chengdu, 610036, China
The Second Xiangya Hospital of Central South University
RECRUITING

Changsha, 410011, China
The Seventh People's Hospital of Hangzhou
RECRUITING

Hangzhou, 310000, China
Tianjin Anding Hospital
RECRUITING

Tianjin, 300022, China
Tri-Service General Hospital
NOT_YET_RECRUITING

Taipei, 114, Taiwan
Trial Tech
RECRUITING

Curitiba, 80240-280, Brazil
Uematsu Mental Clinic
RECRUITING

Chikugo, 833-0041, Japan
University of Massachusetts Chan Medical School
RECRUITING

Worcester, Massachusetts, 01655, United States
University of Oregon
RECRUITING

Eugene, Oregon, 97403, United States
Vital Medical Research
RECRUITING

Miami, Florida, 33174, United States
Wellness Research Center
RECRUITING

Miami, Florida, 33135, United States
Wuhu Hospital of Beijing Anding hospital
RECRUITING

Wuhu, 242407, China
Xi An Mental Health Center
RECRUITING

Xi'an, 710061, China
Yale University School of Medicine
RECRUITING

New Haven, Connecticut, 06511, United States
Yamagata Sakuracho Hospital
NOT_YET_RECRUITING

Yamagata, 990-0045, Japan
Yuge Hospital
NOT_YET_RECRUITING

Kumamoto, 861-8002, Japan
Yutaka Clinic
NOT_YET_RECRUITING

Sagamihara, 252-0303, Japan
Zhumadian Psychiatric Hospital
RECRUITING

Zhumadian, 463000, China

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