New trial aims to spare breast cancer patients from arm swelling

NCT ID NCT07140172

First seen Jun 27, 2026 · Last updated Aug 07, 2026 · Updated 1 time

Summary

This study compares two ways to treat breast cancer that has spread to nearby lymph nodes: targeted radiotherapy or surgical removal of the nodes. The goal is to see which approach better preserves arm function and reduces the risk of long-term arm swelling. About 1,060 adults with node-positive breast cancer will take part.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • "Alexandra" Hospital, Athens

    NOT_YET_RECRUITING

    Athens, Greece

  • Beaumont Hospital Dublin

    NOT_YET_RECRUITING

    Dublin, Ireland

  • Bethesda Hospital Basel

    RECRUITING

    Pratteln, Switzerland

  • Breast Center Osnabrück

    RECRUITING

    Osnabrück, Germany

  • Breast Centre of Clinical Hospital, Rijeka

    NOT_YET_RECRUITING

    Rijeka, Croatia

  • Breast Surgery Service, University Hospital Basel

    RECRUITING

    Basel, 4031, Switzerland

  • Brustzentrum Heidelberg Klinik St. Elisabeth GmbH

    RECRUITING

    Heidelberg, Germany

  • Brustzentrum Zürich (Seefeld)

    RECRUITING

    Zurich, 8008, Switzerland

  • CIUSSS du Centre Ouest-de-l 'Ile-de-Montréal

    RECRUITING

    Montreal, Canada

  • Centro di Senologia della Svizzera Italiana

    RECRUITING

    Lugano, Switzerland

  • Clinique de Genolier

    RECRUITING

    Genolier, Switzerland

  • Clinique des Grangettes

    RECRUITING

    Chêne-Bougeries, 1224, Switzerland

  • Cork University Hospital

    NOT_YET_RECRUITING

    Cork, Ireland

  • Duke University/Duke Cancer Center

    NOT_YET_RECRUITING

    Durham, North Carolina, 27710, United States

  • Fox Chase Cancer Center

    RECRUITING

    Philadelphia, Pennsylvania, 19111, United States

  • Graubünden Cantonal Hospital

    RECRUITING

    Chur, Switzerland

  • HELIOS Universitätsklinikum Wuppertal

    NOT_YET_RECRUITING

    Wuppertal, Germany

  • Hirslandenklinik St. Anna

    RECRUITING

    Lucerne, Switzerland

  • Hôpital Neuchâtelois

    RECRUITING

    Neuchâtel, Switzerland

  • Hôpital du Valais, Hôpital de Sion

    RECRUITING

    Sion, Switzerland

  • Hôpitaux Universitaires de Genève

    RECRUITING

    Geneva, Switzerland

  • Istituto Oncologico Veneto IRCCS

    NOT_YET_RECRUITING

    Padova, Italy

  • KH Dornbirn

    RECRUITING

    Dornbirn, Austria

  • Kantonsspital Baden

    RECRUITING

    Baden, Switzerland

  • Kantonsspital Luzern

    RECRUITING

    Lucerne, Switzerland

  • Kantonsspital St. Gallen

    RECRUITING

    Sankt Gallen, Switzerland

  • Kantonsspital Winterthur

    RECRUITING

    Winterthur, Switzerland

  • LKH Feldkirch

    RECRUITING

    Feldkirch, Austria

  • MUI - Univ. Klinik f. Frauenheilkunde Innsbruck

    RECRUITING

    Innsbruck, Austria

  • Medical University Vienna, Department of Gynecology

    NOT_YET_RECRUITING

    Vienna, Austria

  • Medical University Vienna, Department of Surgery

    RECRUITING

    Vienna, Austria

  • Ordensklinikum Linz

    RECRUITING

    Linz, Austria

  • Pauls Stradiņš Clinical University Hospital

    RECRUITING

    Riga, Latvia

  • Policlinico Universitario "Agostino Gemelli

    NOT_YET_RECRUITING

    Rome, Italy

  • Sancaktepe Şehit Prof. Dr. İlhan Varank Training and Research Hospital

    NOT_YET_RECRUITING

    Istanbul, Turkey (Türkiye)

  • Schaffhausen Cantonal Hospital

    RECRUITING

    Schaffhausen, Switzerland

  • Spital Limmattal

    RECRUITING

    Schlieren, Switzerland

  • Spital Thurgau

    RECRUITING

    Frauenfeld, 8500, Switzerland

  • Spital Zollikerberg

    RECRUITING

    Zollikerberg, Switzerland

  • St- Luke's Hospital Dublin

    NOT_YET_RECRUITING

    Dublin, Ireland

  • St. James's Hospital Dublin

    NOT_YET_RECRUITING

    Dublin, Ireland

  • St. Vincent's University Hospital

    NOT_YET_RECRUITING

    Dublin, Ireland

  • Stadtspital Triemli

    RECRUITING

    Zurich, Switzerland

  • Swedish Cancer Institute

    NOT_YET_RECRUITING

    Seattle, Washington, 98104, United States

  • Ticino Breast Center

    NOT_YET_RECRUITING

    Lugano, Switzerland

  • Tumor-& Brustzentrum Ostschweiz St. Gallen

    RECRUITING

    Sankt Gallen, Switzerland

  • University Hospital Galway

    RECRUITING

    Galway, Ireland

  • University Hospital Heidelberg, Women's Clinic

    RECRUITING

    Heidelberg, 69120, Germany

  • University Hospital Zürich

    NOT_YET_RECRUITING

    Zurich, Switzerland

  • University Hospital of Bern (Inselspital)

    NOT_YET_RECRUITING

    Bern, Switzerland

  • University Hospital of Heraklion

    NOT_YET_RECRUITING

    Heraklion, Greece

  • University Hospital of Larissa

    NOT_YET_RECRUITING

    Larissa, Greece

  • Walter Reed National Military Medical Center

    NOT_YET_RECRUITING

    Bethesda, Maryland, 20814, United States

  • İstanbul Bağcılar Training and Research Hospital

    NOT_YET_RECRUITING

    Istanbul, Turkey (Türkiye)

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Other studies related to the condition(s) this trial covers.