New study tracks Real-World effects of breast cancer drug in 800 patients

NCT ID NCT05573893

Recruiting now Knowledge-focused Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 13, 2026 · Updated 3 times

Summary

This study is observing about 800 adults with advanced breast cancer (HER2-positive, low, or ultralow) who are receiving the drug trastuzumab deruxtecan as part of their normal care in Germany. Researchers are tracking how long patients stay on the drug before switching treatments and how their quality of life changes. The goal is to gather real-world data on the drug's effectiveness and safety outside of a controlled trial.

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Conditions

The condition(s) this trial relates to.

breast cancer breast carcinoma breast neoplasm HER2 positive breast carcinoma metastatic neoplasm Neoplasm Metastasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST CANCER BREAST NEOPLASMS NEOPLASM METASTASIS

Contacts and locations

Locations

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Amberg, 92224, Germany
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Ansbach, 91522, Germany
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Apolda, 99510, Germany
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Aschaffenburg, 63739, Germany
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Augsburg, 86150, Germany
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Augsburg, 86156, Germany
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Bad Reichenhall, 83435, Germany
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Baden-Baden, 76532, Germany
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Balingen, 72336, Germany
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Bamberg, 96049, Germany
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Berlin, 10117, Germany
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Berlin, 10367, Germany
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Berlin, 10715, Germany
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Berlin, 12623, Germany
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Berlin, 13125, Germany
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Bielefeld, 33604, Germany
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Bonn, 53111, Germany
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Brandenburg an der Havel, 14770, Germany
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Braunschweig, 38100, Germany
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Bremen, 28209, Germany
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Bremerhaven, 27574, Germany
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Coburg, 96450, Germany
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Dessau, 6847, Germany
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Donauwörth, 86609, Germany
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Dortmund, 44137, Germany
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Dresden, 1127, Germany
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Dresden, 1307, Germany
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Düsseldorf, 40235, Germany
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Eggenfelden, 84307, Germany
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Erfurt, 99085, Germany
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Essen, 45147, Germany
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Filderstadt - Bonlanden, 70794, Germany
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Frankfurt, 60389, Germany
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Freudenstadt, 72250, Germany
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Fürstenfeldbruck, 82256, Germany
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Fürstenwalde, 15517, Germany
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Gerlingen, 70839, Germany
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Giessen, 35392, Germany
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Halle, 6110, Germany
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Hamburg, 20259, Germany
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Hamburg, 21073, Germany
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Hanover, 30161, Germany
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Hanover, 30449, Germany
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Hansestadt Salzwedel, 29410, Germany
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Heidenheim, 89522, Germany
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Heilbronn, 74078, Germany
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Hildesheim, 31134, Germany
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Homburg/Saar, 66421, Germany
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Jena, 7747, Germany
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Kaiserslautern, 67655, Germany
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Karlsruhe, 76135, Germany
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Kassel, 34117, Germany
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Kassel, 34125, Germany
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Kempten, 87439, Germany
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Kiel, 24116, Germany
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Krefeld, 47805, Germany
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Kulmbach, 95326, Germany
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Landshut, 84036, Germany
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Leer, 26789, Germany
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Leipzig, 4103, Germany
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Loerrach, 79539, Germany
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Lübeck, 23562, Germany
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Lüneburg, 21339, Germany
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Magdeburg, 39130, Germany
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Mainz, 55131, Germany
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Marburg, 35037, Germany
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Memmingen, 87700, Germany
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Mönchengladbach, 41061, Germany
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Mutlangen, 73557, Germany
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Mühlhausen, 99974, Germany
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München, 80638, Germany
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München, 80639, Germany
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München, 81377, Germany
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Neumarkt, 92318, Germany
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Neuruppin, 16816, Germany
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Neustadt am Rübenberge, 31535, Germany
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Nordhausen, 99734, Germany
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Nuremberg, 90419, Germany
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Oldenburg, 26121, Germany
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Oranienburg, 16515, Germany
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Potsdam, 14467, Germany
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Recklinghausen, 45659, Germany
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Regensburg, 93053, Germany
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Rosenheim, 83022, Germany
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Rotenburg (Wümme), 27356, Germany
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Saalfeld, 7318, Germany
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Saarbrücken, 66113, Germany
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Schwäbisch Hall, 74523, Germany
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Siegen, 57072, Germany
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Singen, 78224, Germany
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Solingen, 42653, Germany
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Stade, 21680, Germany
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Stuttgart, 70199, Germany
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Torgau, 4860, Germany
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Troisdorf, 53840, Germany
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Ulm, 89073, Germany
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Ulm, 89075, Germany
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Walsrode, 29664, Germany
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Weiden, 92637, Germany
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Weinheim, 69469, Germany
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Wessenfels, 6667, Germany
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Westerstede, 26655, Germany
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Wiesbaden, 65199, Germany
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Winnenden, 71364, Germany
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Witten, 58452, Germany
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Wolfsburg, 38440, Germany
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Wuppertal, 42283, Germany
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Würzburg, 97080, Germany
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Zittau, 02763, Germany

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