Simple blood test could predict breast cancer return

NCT ID NCT07211178

Recruiting now Knowledge-focused Sponsor: Tempus AI Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is looking at whether a simple blood test can find tiny bits of cancer DNA left in the body after breast cancer treatment. These leftover cells, called minimal residual disease (MRD), can sometimes cause the cancer to come back. The study will follow 900 breast cancer patients over time to see if the test results can predict recurrence and help doctors make better treatment decisions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help doctors better predict if breast cancer will return and guide more personalized follow-up care.
What could go wrong: This is an observational study, not testing a treatment. It may not directly improve outcomes, and results may take years to apply in practice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm HER2 positive breast carcinoma hormone receptor-positive breast cancer Neoplasm, Residual triple-negative breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST CANCER EARLY-STAGE BREAST CANCER HER2 + BREAST CANCER HR POSITIVE/HER-2 NEGATIVE BREAST CANCER TNBC - TRIPLE-NEGATIVE BREAST CANCER

Contacts and locations

Locations

Birmingham Hematology Associates
RECRUITING

Birmingham, Alabama, 35223, United States
Cancer Care Northwest
RECRUITING

Spokane Valley, Washington, 99216, United States
Cancer Care Specialist of Illinois
RECRUITING

O'Fallon, Illinois, 62269, United States
Cancer Care Specialist of Reno
RECRUITING

Reno, Nevada, 89511, United States
Cleveland Clinic Florida
RECRUITING

Weston, Florida, 33331, United States
Goshen Center for Cancer Care
RECRUITING

Goshen, Indiana, 46526, United States
Gunderson Health
RECRUITING

La Crosse, Wisconsin, 54601, United States
Nashville General
RECRUITING

Nashville, Tennessee, 37208, United States
Oncology Hematology Associates
RECRUITING

Springfield, Missouri, 65807, United States
PIH Health Whittier Hospital
RECRUITING

Whittier, California, 90602, United States
Southern Illinois Hospital Services
RECRUITING

Carbondale, Illinois, 62902, United States
Summit Medical Group
RECRUITING

Florham Park, New Jersey, 07932, United States
Trinity Health
RECRUITING

Ann Arbor, Michigan, 48106, United States
University of Cincinnati Medical Center
RECRUITING

Cincinnati, Ohio, 45219, United States

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