First test of new drug duo aims to shrink breast tumors before surgery

NCT ID NCT04481113

Summary

This early-stage study tested the safety and best dose of two oral drugs, abemaciclib and niraparib, given together before surgery for certain types of breast cancer. The goal was to see if this combination could shrink tumors effectively with manageable side effects. The study involved a small group of 8 participants with hormone receptor-positive, HER2-negative breast cancer.

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Contacts and locations

Locations

  • OHSU Knight Cancer Institute

    Portland, Oregon, 97239, United States

Conditions

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