New hope for Tough-to-Treat breast cancer? scientists test Triple-Threat drug combo
NCT ID NCT03939897
Summary
This study is testing if adding a new drug called copanlisib to the standard two-drug treatment (fulvestrant and abemaciclib) is more effective for advanced breast cancer that has stopped responding to hormone therapy. It will involve about 24 patients with hormone-positive, HER2-negative breast cancer that has spread. The main goal is to find the safest dose of the three-drug combination and see if it works better to control the cancer.
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Contacts and locations
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Locations
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Bellevue Hospital Center
New York, New York, 10016, United States
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Laura and Isaac Perlmutter Cancer Center at NYU Langone
New York, New York, 10016, United States
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Ohio State University Comprehensive Cancer Center
Columbus, Ohio, 43210, United States
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Siteman Cancer Center at Christian Hospital
St Louis, Missouri, 63136, United States
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Siteman Cancer Center at Saint Peters Hospital
City of Saint Peters, Missouri, 63376, United States
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Siteman Cancer Center at West County Hospital
Creve Coeur, Missouri, 63141, United States
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Siteman Cancer Center-South County
St Louis, Missouri, 63129, United States
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UC Irvine Health Cancer Center-Newport
Costa Mesa, California, 92627, United States
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UC Irvine Health/Chao Family Comprehensive Cancer Center
Orange, California, 92868, United States
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University of Alabama at Birmingham Cancer Center
Birmingham, Alabama, 35233, United States
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University of Kentucky/Markey Cancer Center
Lexington, Kentucky, 40536, United States
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Wake Forest University Health Sciences
Winston-Salem, North Carolina, 27157, United States
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Wake Forest University at Clemmons
Clemmons, North Carolina, 27012, United States
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Washington University School of Medicine
St Louis, Missouri, 63110, United States
Conditions
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