Radiation's hidden toll on the brain: new study maps cognitive changes to protect patients

NCT ID NCT05576103

Recruiting now Knowledge-focused Sponsor: Jona Hattangadi-Gluth Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study follows 300 adults with primary brain tumors (such as glioma or meningioma) who are receiving partial brain radiation. Researchers use brain scans and memory, attention, and language tests before and after treatment to understand how radiation affects thinking skills. The goal is to link radiation doses to specific brain changes, which could help design future treatments that better preserve cognitive function.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: fractionated partial brain radiotherapy
What this could lead to: If successful, this research could guide doctors to adjust radiation plans to better protect memory and thinking skills in future brain tumor patients.
What could go wrong: This is an observational study, not a treatment trial. It will not directly benefit participants and may not lead to changes in standard care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

brain cancer glioma meningioma Neurilemmoma primary brain neoplasm schwannoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GLIOMA MENINGIOMA PRIMARY BRAIN TUMOR SCHWANNOMA

Contacts and locations

Locations

Moores Cancer Center
RECRUITING

San Diego, California, 92037, United States

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