Radiation's hidden toll on the brain: new study maps cognitive changes to protect patients

NCT ID NCT05576103

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study follows 300 adults with primary brain tumors (such as glioma or meningioma) who are receiving partial brain radiation. Researchers use brain scans and memory, attention, and language tests before and after treatment to understand how radiation affects thinking skills. The goal is to link radiation doses to specific brain changes, which could help design future treatments that better preserve cognitive function.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

fractionated partial brain radiotherapy

What this could lead to

If successful, this research could guide doctors to adjust radiation plans to better protect memory and thinking skills in future brain tumor patients.

What could go wrong

This is an observational study, not a treatment trial. It will not directly benefit participants and may not lead to changes in standard care.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

brain cancer glioma meningioma Neurilemmoma primary brain neoplasm schwannoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Moores Cancer Center

    RECRUITING

    San Diego, California, 92037, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••