Cure My Disease

Don't miss your cure!

 Log in / Sign up

Can zapping two brain areas beat OCD?

NCT ID NCT04958096

Recruiting now Disease control Sponsor: Andrew Moses Lee, MD, PhD Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing whether adding stimulation to the front part of the brain can improve standard deep brain stimulation (DBS) for severe obsessive-compulsive disorder (OCD). Fifteen adults with OCD that hasn't improved with other treatments will get DBS plus an extra set of electrodes in the prefrontal or cingulate cortex. Researchers will track brain signals and OCD symptoms for up to two years to see if the extra stimulation helps.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
deep brain stimulation and cortical stimulation
What this could lead to
If successful, this could point toward a more effective brain stimulation treatment for severe OCD that doesn't respond to other therapies.
What could go wrong
This is a very early, small study with only 15 people. It's testing a new combination of brain stimulation, so it may not work better than standard DBS, and there are surgical risks from implanting extra electrodes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for OBSESSIVE-COMPULSIVE DISORDER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Compulsive Behavior obsessive-compulsive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OBSESSIVE-COMPULSIVE DISORDER

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • UCSF Nancy Friend Pritzker Psychiatry Building

    RECRUITING

    San Francisco, California, 94107, United States

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

More trials for these conditions

Other studies related to the condition(s) this trial covers.