Could a gentle brain zap ease MS fatigue?
NCT ID NCT07438964
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a mild electrical current applied to the front of the brain for 20 minutes a day over five days can reduce central fatigue in people with relapsing-remitting multiple sclerosis. Researchers will use brain scans and blood tests to see if the stimulation changes inflammation and reward-related brain activity. The trial includes 84 participants and will follow up for four weeks after treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
transcranial direct current stimulation (tDCS)
What this could lead to
If it works, this could point toward a non-drug treatment for central fatigue in multiple sclerosis.
What could go wrong
This is an early, small study (84 people) testing a short-term intervention. The effect may be small or not last, and fatigue is complex with many causes.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Email: •••••@•••••
Locations
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Charité Campus Mitte
RECRUITINGBerlin, State of Berlin, 10117, Germany
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact