Can magnetic pulses sharpen aging brains? new trial aims to find out.

NCT ID NCT05460468

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study uses a noninvasive technique called transcranial magnetic stimulation (TMS) to try to improve working memory in healthy older adults and people with mild cognitive impairment (MCI). Researchers will use brain scans to personalize the stimulation and measure its effects on memory tasks and brain activity. The goal is to learn whether this approach can reliably enhance memory and guide future treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Transcranial Magnetic Stimulation (TMS)

What this could lead to

If successful, this could point toward a noninvasive brain stimulation treatment to boost memory in older adults and those with mild cognitive impairment.

What could go wrong

This is an early-stage study focused on understanding brain networks, not a proven treatment. The approach may not translate into lasting memory benefits.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Cognitive Dysfunction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Duke University Hospital

    RECRUITING

    Durham, North Carolina, 27710, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••