New brain zaps aim to lift depression when meds fail

NCT ID NCT07329153

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests two types of brain stimulation for people with depression that hasn't improved with medication. About 247 adults will receive either a precise, guided form of stimulation, a standard form, or a fake (sham) procedure. The goal is to see if these treatments can safely reduce depression symptoms.

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Conditions

The condition(s) this trial relates to.

Depression Depressive Disorder, Treatment-Resistant

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Cornell University

    New York, New York, 10065, United States

    Contact Email: •••••@•••••

  • University of California at San Diego (UCSD)

    San Diego, California, 92127, United States

    Contact Email: •••••@•••••

  • University of Texas Southwestern Medical Center

    Dallas, Texas, 75390, United States

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