Zapping the brain to rebuild leg muscle after ACL tears

NCT ID NCT07128602

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

After ACL surgery, many women have long-term thigh muscle weakness because the brain doesn't send strong enough signals to the muscle. This study tests whether a gentle, non-invasive brain stimulation (tDCS) during rehab exercises can boost those signals and improve strength. 42 women aged 18-35, 2-6 months after ACL reconstruction, will receive either real or sham stimulation over 6 sessions while doing thigh exercises. Researchers will measure muscle strength, speed, and brain activity to see if the stimulation helps.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

transcranial direct current stimulation (tDCS)

What this could lead to

If it works, this could lead to a new rehab method that helps women regain thigh strength faster after ACL surgery.

What could go wrong

This is a small, early-stage study with only 42 participants. The brain stimulation may not produce meaningful improvements over standard rehab.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Ryan Zarzycki

    RECRUITING

    Glenside, Pennsylvania, 19038, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••