Zapping the brain to rebuild leg muscle after ACL tears

NCT ID NCT07128602

Recruiting now Symptom relief Sponsor: Arcadia University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

After ACL surgery, many women have long-term thigh muscle weakness because the brain doesn't send strong enough signals to the muscle. This study tests whether a gentle, non-invasive brain stimulation (tDCS) during rehab exercises can boost those signals and improve strength. 42 women aged 18-35, 2-6 months after ACL reconstruction, will receive either real or sham stimulation over 6 sessions while doing thigh exercises. Researchers will measure muscle strength, speed, and brain activity to see if the stimulation helps.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: transcranial direct current stimulation (tDCS)
What this could lead to: If it works, this could lead to a new rehab method that helps women regain thigh strength faster after ACL surgery.
What could go wrong: This is a small, early-stage study with only 42 participants. The brain stimulation may not produce meaningful improvements over standard rehab.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION REHABILITATION QUADRICEPS MUSCLE FUNCTION

Zapping the brain to rebuild leg muscle after ACL tears

Summary

What this could mean

Get notified about this study

As listed by the trial registrant

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