Can brain scans predict radiation success? new trial aims to find out

NCT ID NCT04197297

Recruiting now Knowledge-focused Sponsor: University Health Network, Toronto Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 2 trial is testing whether CT and MRI scans can act as biomarkers to predict how patients with brain metastases respond to radiation therapy. About 90 adults with brain metastases who are scheduled for radiation will get scans before and after treatment. The goal is to validate imaging biomarkers that could one day help guide personalized treatment decisions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help doctors personalize radiation treatment for brain metastasis patients based on imaging biomarkers.
What could go wrong: This is an early-phase trial with only 90 participants, so results may not apply to all patients. The study focuses on measuring biomarkers, not on testing a new treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

brain cancer metastatic malignant neoplasm in the brain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BRAIN METASTASES, ADULT

Contacts and locations

Locations

University Health Network
RECRUITING

Toronto, Ontario, L4W4C2, Canada

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