Fewer days of radiation may control brain tumors just as well

NCT ID NCT07167134

First seen Jun 26, 2026 ยท Last updated Jun 26, 2026

Summary

This phase 3 trial compares two radiation schedules for people with 1 to 5 brain metastases from cancers like melanoma, kidney, or sarcoma. One group gets radiation on days 1, 3, and 5; the other on days 1, 2, and 3. The goal is to see if the shorter schedule controls tumor growth as well or better at 6 months, while reducing treatment burden.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
radiation therapy
What this could lead to
If successful, this could offer a more convenient and equally effective radiotherapy schedule for patients with hard-to-treat brain metastases.
What could go wrong
This is a phase 3 trial, but it only compares two radiation schedules; it does not test a new drug or cure. The benefit may be modest, and results may not apply to all brain metastasis types.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • ICANS

    Strasbourg, France

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Other studies related to the condition(s) this trial covers.