Can more radiation sessions tame large brain tumors safely?
NCT ID NCT03412812
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether giving higher doses of radiation over five sessions is safe for people with brain metastases that are 2 to 6 cm in size. These larger tumors are often too risky for a single high-dose treatment. The trial enrolled 13 adults and aimed to find the highest dose that does not cause severe side effects.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
radiation therapy
What this could lead to
If successful, this could establish a safer, more effective radiation dose for treating larger brain tumors that are not good candidates for single-session radiosurgery.
What could go wrong
This is a very early, small (13 participants) dose-finding study, not a large efficacy trial. The results may not apply to all patients, and there is a risk of radiation-related brain swelling or other toxicity.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Hazelrig-Salter Radiation Oncology Center
Birmingham, Alabama, 35233, United States