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Brain scans reveal inflammation clues in Parkinson's

NCT ID NCT05205291

Recruiting now Knowledge-focused Sponsor: University of Exeter Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 37 times

Summary

This study aims to understand how inflammation in the brain contributes to Parkinson's disease. Researchers will give a mild inflammatory substance (LPS) to 30 participants, including people with Parkinson's, those with REM sleep behavior disorder, and healthy volunteers. They will use special PET and MRI scans to measure brain inflammation before and after the LPS injection, along with blood tests. The goal is to learn more about the role of inflammation in Parkinson's, not to provide a treatment.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Exeter

    RECRUITING

    Exeter, United Kingdom

    Contact

    Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.

NEURODEGENERATIVE DISEASES PARKINSON DISEASE REM SLEEP BEHAVIOR DISORDER (IRBD) REM SLEEP BEHAVIOR DISORDER (IRBD)