Brain scans in the NICU could help protect preemie brains

NCT ID NCT06052865

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study uses repeated MRI scans to track brain injury and growth in very preterm babies (born before 33 weeks) during their NICU stay. Researchers will also test a program called SENSE-plus, which involves daily gentle sensory activities like touch and sound, to see if it helps brain development. The goal is to better identify high-risk infants and guide early interventions to improve their long-term outcomes.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
SENSE-plus (SENSE II program) - a behavioral intervention involving daily sensory exposures for preterm infants
What this could lead to
If successful, this could help doctors identify preterm infants at highest risk for brain injury early, and tailor rehabilitation to improve their development.
What could go wrong
This is an observational study with a small group (75 infants) and no control group, so results may not apply to all preterm babies. The intervention is exploratory and not proven to change outcomes.

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Conditions

The condition(s) this trial relates to.

brain injury Premature Birth

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

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