Breast cancer Drug's brain impact under scrutiny in new study

NCT ID NCT04297020

Recruiting now Knowledge-focused Sponsor: Jonsson Comprehensive Cancer Center Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jul 08, 2026 · Updated 3 times

Summary

This study looks at how endocrine therapy, a common breast cancer treatment, affects thinking and brain function in 120 survivors aged 35-65. Researchers will use brain scans and memory tests to compare survivors on therapy with healthy women. The goal is to understand if menopause status plays a role in these effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could clarify how endocrine therapy impacts brain health, guiding better treatment decisions for breast cancer survivors.
What could go wrong: This is an observational study with no direct treatment, so it won't change care immediately. Results may not apply to all survivors due to the small, specific group studied.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm Cognitive Dysfunction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COGNITIVE FUNCTION COGNITIVE IMPAIRMENT

Contacts and locations

Locations

University of California at Los Angeles
RECRUITING

Los Angeles, California, 90095, United States

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