Brain scans reveal energy clues in schizophrenia

NCT ID NCT06236048

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study compares brain energy use, lactate, and glutamate levels in 75 people with schizophrenia and healthy volunteers using advanced MRI and PET scans. Researchers aim to see if brain glucose use is lower and lactate higher in schizophrenia, and if glutamate varies more. No treatment is given; it is purely observational to gather knowledge.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could help researchers better understand how brain energy and glutamate relate to schizophrenia, potentially guiding future treatments.

What could go wrong

This is an observational study, not a treatment trial. It is small (75 participants) and early-stage, so findings may not apply broadly or lead directly to new therapies.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

schizophrenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • South London and the Maudsley NHS Foundation Trust

    RECRUITING

    London, United Kingdom

    Contact