Brain tumor inflammation seen in real time with new imaging agent

NCT ID NCT07462507

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing a new radioactive tracer called [C-11]-CS1P1 that lights up inflammation in brain tumors during a PET scan. Researchers will scan 104 adults with primary or secondary brain cancers before and after treatment to see how inflammation patterns change. The goal is to better understand the role of inflammation in these tumors and how it relates to MRI findings and patient outcomes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
[C-11]-CS1P1 (a radioactive tracer for PET scans)
What this could lead to
If successful, this could help doctors better understand inflammation in brain tumors and improve how they monitor treatment response.
What could go wrong
This is an early-phase imaging study, not a treatment trial. It may not lead to direct patient benefits, and the tracer's usefulness in routine care is uncertain.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Washington University School of Medicine

    RECRUITING

    St Louis, Missouri, 63110, United States

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