New hope for kids with devastating brain cancer: trial tests Life-Extending drug combos

NCT ID NCT05843253

Summary

This study is testing two different drug combinations to see if they can help children and young adults with aggressive brain tumors live longer. The trial is for patients who have just finished radiation therapy. One group receives two drugs (ribociclib and everolimus), while another group receives a different pair (ribociclib and temozolomide), depending on the specific genetic changes found in their tumor.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Ann & Robert H. Lurie Children's Hospital of Chicago

    RECRUITING

    Chicago, Illinois, 60611, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • C.S. Mott Children's Hospital

    RECRUITING

    Ann Arbor, Michigan, 48109, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Children's Hospital Colorado

    NOT_YET_RECRUITING

    Aurora, Colorado, 80045, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Children's Hospital of Philadelphia

    NOT_YET_RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Children's National Medical Center

    RECRUITING

    Washington D.C., District of Columbia, 20010, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Cincinnati Children's Hospital Medical Center

    RECRUITING

    Cincinnati, Ohio, 45229, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Dana-Farber Cancer Institute

    NOT_YET_RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Duke University Health System

    RECRUITING

    Durham, North Carolina, 27708, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Great Ormond Street Hospital

    NOT_YET_RECRUITING

    London, WC1N 3JH, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hopp Children's Cancer Center at NCT Heidelberg (KiTZ)

    NOT_YET_RECRUITING

    Heidelberg, Baden-Wurttemberg, 69120, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Montreal Children's Hospital

    NOT_YET_RECRUITING

    Montreal, Quebec, H4A3J1, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Nationwide Children's Hospital

    RECRUITING

    Columbus, Ohio, 43235, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Perth Children's Hospital

    RECRUITING

    Perth, Western Australia, 6000, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Princess Máxima Center

    NOT_YET_RECRUITING

    Utrecht, 3720, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Queensland Children's Hospital

    NOT_YET_RECRUITING

    South Brisbane, Queensland, 4101, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Royal Children's Hospital

    RECRUITING

    Melbourne, Victoria, 3052, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Seattle Children's Hospital

    RECRUITING

    Seattle, Washington, 98105, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Starship Children's Hospital

    NOT_YET_RECRUITING

    Auckland, Grafton, 1023, New Zealand

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Sydney Children's Hospital

    RECRUITING

    Randwick, New South Wales, 2031, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Texas Children's Hospital

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Hospital for Sick Children (SickKids)

    NOT_YET_RECRUITING

    Toronto, Ontario, M5G1X8, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.