WHO GRADE IV GLIOMA
Clinical trials for WHO GRADE IV GLIOMA explained in plain language.
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Promising drug cocktail targets tough brain cancers in kids
Disease control Recruiting nowThis study tests two drug combinations given after radiation for children and young adults with aggressive brain tumors (high-grade glioma or DIPG). One group receives ribociclib plus everolimus; another gets ribociclib plus temozolomide. The goal is to see if these combinations …
Matched conditions: WHO GRADE IV GLIOMA
Phase: PHASE2 • Sponsor: Nationwide Children's Hospital • Aim: Disease control
Last updated May 17, 2026 01:03 UTC
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New drug hope for kids with rare brain tumors
Disease control Recruiting nowThis study tests the drug lorlatinib in children (ages 1 to 21) with a newly diagnosed high-grade glioma that has a specific genetic change (ALK or ROS1 fusion). The goal is to see if the drug can shrink or control the tumor and to check its safety when given with or after other …
Matched conditions: WHO GRADE IV GLIOMA
Phase: EARLY_PHASE1 • Sponsor: Nationwide Children's Hospital • Aim: Disease control
Last updated May 17, 2026 01:00 UTC
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Brain tumor genetics could unlock personalized treatments for kids
Knowledge-focused Recruiting nowThis study is for children, teens, and young adults (ages 1 to 39) newly diagnosed with a high-grade glioma, a serious type of brain tumor. Researchers will analyze the tumor's genetic makeup to see if it matches a specific treatment plan in a future study. The goal is to learn m…
Matched conditions: WHO GRADE IV GLIOMA
Sponsor: Nationwide Children's Hospital • Aim: Knowledge-focused
Last updated May 17, 2026 01:00 UTC