New universal flu vaccine enters human testing

NCT ID NCT07215858

First seen Jun 27, 2026 · Last updated Jul 01, 2026 · Updated 3 times

Summary

This study tests an experimental flu vaccine called BPL-1357, given as a shot or nasal spray, to see if it is safe and can protect against multiple flu types. About 129 healthy adults aged 18-55 will receive the vaccine or a placebo, then be exposed to a flu virus in a controlled setting. The goal is to find a vaccine that works against seasonal and pandemic flu strains.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

BPL-1357 (a whole-virus flu vaccine given as a shot or nasal spray)

What this could lead to

If successful, this vaccine could provide broader protection against different flu strains, potentially helping to prevent future flu pandemics.

What could go wrong

This is an early phase 2 trial with only 129 participants, so results may not apply to everyone. The vaccine may not work as hoped, and side effects are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for INFLUENZA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

human disease influenza prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Texas Medical Branch, Galveston

    NOT_YET_RECRUITING

    Galveston, Texas, 77555, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••